PURPOSE: The value of the ERG scotopic threshold response (STR), which is known to originate in the proximal retina and of the near-threshold scotopic PII(B-wave), was studied in glaucoma. METHODS: Full-field single flashes were presented under scotopic conditions in two subject groups, a glaucoma group (n = 30) and a normal control group (n = 35). The intensity level for evoking STR was where the maximum response occurs, whereas the intensity level for evoking scotopic PII was where the response begins to appear. RESULTS: The STR is only slightly reduced in glaucoma (P = 0.046), but scotopic PII is significantly diminished (P < 0.0001). CONCLUSIONS: The relatively intact STR in glaucoma suggests that structures responsible for its generation are less damaged in glaucoma than those responsible for scotopic PII.
PURPOSE: The value of the ERG scotopic threshold response (STR), which is known to originate in the proximal retina and of the near-threshold scotopic PII(B-wave), was studied in glaucoma. METHODS: Full-field single flashes were presented under scotopic conditions in two subject groups, a glaucoma group (n = 30) and a normal control group (n = 35). The intensity level for evoking STR was where the maximum response occurs, whereas the intensity level for evoking scotopic PII was where the response begins to appear. RESULTS: The STR is only slightly reduced in glaucoma (P = 0.046), but scotopic PII is significantly diminished (P < 0.0001). CONCLUSIONS: The relatively intact STR in glaucoma suggests that structures responsible for its generation are less damaged in glaucoma than those responsible for scotopic PII.
Authors: Laura Fernández-Sánchez; Luis Pérez de Sevilla Müller; Nicholas C Brecha; Nicolás Cuenca Journal: Invest Ophthalmol Vis Sci Date: 2014-08-12 Impact factor: 4.799
Authors: Nina Wakili; Folkert K Horn; Anselm G Jünemann; Nhung X Nguyen; Christian Y Mardin; Matthias Korth; Jan Kremers Journal: Doc Ophthalmol Date: 2008-02-14 Impact factor: 2.379
Authors: Manuel Salinas-Navarro; Luis Alarcón-Martínez; Francisco Javier Valiente-Soriano; Arturo Ortín-Martínez; Manuel Jiménez-López; Marcelino Avilés-Trigueros; María Paz Villegas-Pérez; Pedro de la Villa; Manuel Vidal-Sanz Journal: Mol Vis Date: 2009-12-05 Impact factor: 2.367