| Literature DB >> 810811 |
G L Curtis, F Stenbäck, W L Ryan.
Abstract
The immune competence of mice during initiation-promotion skin carcinogenesis was determined by skin allograft rejection and lymphocyte mitogenesis. The carcinogen 7, 12-dimethylbenzanthracene inhibited the cellular immune competence of mice while lymphocytes from croton oil treated mice had enhanced PWM response. Chlorphenesin, a stimulator of cellular immunity, was found to inhibit tumorigenesis in initiation-promotion skin carcinogenesis when injected during promotion.Entities:
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Year: 1975 PMID： 810811 DOI： 10.3181/00379727-150-38974
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727