Literature DB >> 114414

Polyadenylate-polyuridylate enhancement of 7,12-dimethylbenz-anthracene skin carcinogenesis.

F Stenbäck, G Curtis, W Ryan.   

Abstract

Double-stranded polynucleotide polyadenylate-polyuridylate (Poly AU) enhanced skin tumor formation in Swiss mice by 75% when injected prior to a single application of 7,12-dimethylbenzanthracene (DMBA). When given after the carcinogen application Poly AU did not significantly enhance tumor formation.

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Year:  1979        PMID: 114414     DOI: 10.1007/bf01963308

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  11 in total

1.  FUNCTION OF DEPRESSED IMMUNOLOGIC REACTIVITY DURING CARCINOGENESIS.

Authors:  R T PREHN
Journal:  J Natl Cancer Inst       Date:  1963-10       Impact factor: 13.506

2.  A continuous high molecular weight base-paired structure is not an absolute requirement for a potential polynucleotide inducer of interferon.

Authors:  M N Thang; L Bachner; E De Clercq; B D Stollar
Journal:  FEBS Lett       Date:  1977-04-15       Impact factor: 4.124

3.  Effects of adjuvants on benzpyrene tumorigenesis in hamsters.

Authors:  H Pinkerton
Journal:  Proc Soc Exp Biol Med       Date:  1972-12

4.  Enhancement of 7,12-dimethylbenzanthracene skin carcinogenesis by adenosine 3',5'-cyclic monophosphate.

Authors:  G L Curtis; F Stenback; W L Ryan
Journal:  Cancer Res       Date:  1974-09       Impact factor: 12.701

5.  Immunologic surveillance at the marcoscopic level: nonselective elimination of premalignant skin papillomas.

Authors:  M A Lappé; R T Prehn
Journal:  Cancer Res       Date:  1969-12       Impact factor: 12.701

6.  Carcinogen-induced immune depression: absence in mice resistant to chemical oncogenesis.

Authors:  O Stutman
Journal:  Science       Date:  1969-10-31       Impact factor: 47.728

7.  Adenyl cyclase activity of spleen cells exposed to immunoenhancing synthetic oligo- and polynucleotides.

Authors:  R Winchurch; M Ishizuka; D Webb; W Braun
Journal:  J Immunol       Date:  1971-05       Impact factor: 5.422

8.  Initiation-promotion skin carcinogenesis and immunological competence.

Authors:  G L Curtis; F Stenbäck; W L Ryan
Journal:  Proc Soc Exp Biol Med       Date:  1975-10

9.  Antibody stimulation of benzo(a)pyrene carcinogenesis.

Authors:  G L Curtis; W L Ryan; F Stenbäck
Journal:  Cancer Lett       Date:  1978-04       Impact factor: 8.679

10.  Regulation of the immune system by synthetic polynucleotides. 3. Action on antigen-reactive cells of thymic origin.

Authors:  R E Cone; A G Johnson
Journal:  J Exp Med       Date:  1971-03-01       Impact factor: 14.307

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  1 in total

Review 1.  Immunomodulatory effects of dsRNA and its potential as vaccine adjuvant.

Authors:  Bo Jin; Tao Sun; Xiao-Hong Yu; Chao-Qun Liu; Ying-Xiang Yang; Ping Lu; Shan-Feng Fu; Hui-Bin Qiu; Anthony E T Yeo
Journal:  J Biomed Biotechnol       Date:  2010-07-05
  1 in total

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