Sexually transmitted diseases and human immunodeficiency virus. Epidemiologic synergy?

HIV infection and STDs are linked by common high risk behaviors. There is increasing evidence, however, that classic STDs and HIV infection interact in a bidirectional and mutually enhancing manner. Several prospective studies have demonstrated that STDs increase the risk of acquisition or transmission of HIV infection. Clinical studies have indicated that HIV infection may affect the clinical presentation, the clinical course, the diagnosis or the response to standard therapy of certain STD's. These studies provide compelling evidence that STD prevention and control are important strategies in HIV prevention.