Literature DB >> 8102053

The blood-brain barrier: morphology, molecules, and neurothelin.

B Schlosshauer1.   

Abstract

The blood-brain barrier (BBB) is a complex structure formed by vascular endothelial cells, which serve to stabilize the homeostasic processes that are essential for neural functioning. The barrier relies on tight junctions between neighboring endothelial cells and a highly restricted passage of blood-borne components through the endothelial lining. Selective transport mechanisms guarantee the essential import and export of metabolites through the BBB into and out of the neural microenvironment. The dual functions of barrier and carrier depend on distinct proteins, some of which have been characterized in detail.

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Year:  1993        PMID： 8102053     DOI： 10.1002/bies.950150508

Source DB:  PubMed          Journal:  Bioessays        ISSN： 0265-9247            Impact factor:   4.345


  28 in total

Review 1.  Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system.

Authors:  Shailendra Joshi; Eugene Ornstein; Jeffrey N Bruce
Journal:  Neurocrit Care       Date:  2007       Impact factor: 3.210

Review 2.  Getting into the brain: approaches to enhance brain drug delivery.

Authors:  Mayur M Patel; Bhoomika R Goyal; Shraddha V Bhadada; Jay S Bhatt; Avani F Amin
Journal:  CNS Drugs       Date:  2009       Impact factor: 5.749

3.  Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.

Authors:  B V Zlokovic; C L Martel; E Matsubara; J G McComb; G Zheng; R T McCluskey; B Frangione; J Ghiso
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-30       Impact factor: 11.205

Review 4.  The anatomy of T-cell activation and tolerance.

Authors:  A Mondino; A Khoruts; M K Jenkins
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-19       Impact factor: 11.205

Review 5.  Mechanisms of dendritic cell trafficking across the blood-brain barrier.

Authors:  Divya Sagar; Catherine Foss; Rasha El Baz; Martin G Pomper; Zafar K Khan; Pooja Jain
Journal:  J Neuroimmune Pharmacol       Date:  2011-08-06       Impact factor: 4.147

Review 6.  Crossing the Blood-Brain Barrier: Recent Advances in Drug Delivery to the Brain.

Authors:  Mayur M Patel; Bhoomika M Patel
Journal:  CNS Drugs       Date:  2017-02       Impact factor: 5.749

Review 7.  Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis.

Authors:  Hu Yang
Journal:  Pharm Res       Date:  2010-07-01       Impact factor: 4.200

8.  Vascular morphogenesis and differentiation after adoptive transfer of human endothelial cells to immunodeficient mice.

Authors:  Dag K Skovseth; Takeshi Yamanaka; Per Brandtzaeg; Eugene C Butcher; Guttorm Haraldsen
Journal:  Am J Pathol       Date:  2002-05       Impact factor: 4.307

9.  Human von Willebrand factor gene sequences target expression to a subpopulation of endothelial cells in transgenic mice.

Authors:  W C Aird; N Jahroudi; H Weiler-Guettler; H B Rayburn; R D Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

10.  Magnesium sulfate treatment in experimental spinal cord injury: emphasis on vascular changes and early clinical results.

Authors:  Erkan Kaptanoglu; Etem Beskonakli; Ihsan Solaroglu; Asuman Kilinc; Yamac Taskin
Journal:  Neurosurg Rev       Date:  2003-05-29       Impact factor: 3.042
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