Literature DB >> 8101831

New markers for linkage analysis of X-linked hypophosphataemic rickets.

P S Rowe1, J Goulding, A Read, R Mountford, A Hanauer, C Oudet, M P Whyte, S Meier-Ewert, H Lehrach, K E Davies.   

Abstract

Three polymorphic markers have been used to improve the genetic map of the region Xp22.1-p22.2, which contains the HYP (hypophosphataemic rickets) locus. DXS365 gave no recombinants with HYP, with a peak Lod score of 5.4 at theta = 0.0. A microsatellite marker mPA274 was derived for the DXS274 locus; it detects five alleles with a polymorphism information content of 0.55. Combining information from this microsatellite and the original DXS274 marker, probe CRI-L1391, the peak Lod score for DXS274 against HYP was 9.6 at theta = 0.02. A microsatellite associated with the DXS207 locus (mPA207) gave a peak lod score against HYP of 4.7 at theta = 0.14. A consideration of key recombinants and multilocus analysis suggests the gene order. Xpter-DXS207-DXS43-DXS197-(DXS365,HYP)- DXS274-DXS41-Xcen.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8101831     DOI： 10.1007/bf00205082

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  17 in total

1.  Refined localization of the gene causing X-linked juvenile retinoschisis.

Authors:  T Alitalo; T A Kruse; A de la Chapelle
Journal:  Genomics       Date:  1991-03       Impact factor: 5.736

2.  Genetic mapping of 12 marker loci in the Xp22.3-p21.2 region.

Authors:  T Alitalo; T A Kruse; P Ahrens; H M Albertsen; A W Eriksson; A de la Chapelle
Journal:  Hum Genet       Date:  1991-04       Impact factor: 4.132

3.  Use of Alu-PCR to characterize hybrids containing multiple fragments and to generate new Xp21.3-p22.2 markers.

Authors:  F Benham; P Rowe
Journal:  Genomics       Date:  1992-02       Impact factor: 5.736

4.  Linkage analysis of two cloned DNA sequences, DXS197 and DXS207, in hypophosphatemic rickets families.

Authors:  R V Thakker; K E Davies; A P Read; P Tippett; C Wooding; T Flint; S Wood; T A Kruse; M P Whyte; J L O'Riordan
Journal:  Genomics       Date:  1990-10       Impact factor: 5.736

5.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

6.  Bridging markers defining the map position of X linked hypophosphataemic rickets.

Authors:  R V Thakker; A P Read; K E Davies; M P Whyte; R Weksberg; F Glorieux; M Davies; R C Mountford; R Harris; A King
Journal:  J Med Genet       Date:  1987-12       Impact factor: 6.318

7.  Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

Authors:  J L Weber; P E May
Journal:  Am J Hum Genet       Date:  1989-03       Impact factor: 11.025

8.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

9.  Mapping of human X-linked hypophosphataemic rickets by multilocus linkage analysis.

Authors:  A P Read; R V Thakker; K E Davies; R C Mountford; D P Brenton; M Davies; F Glorieux; R Harris; G N Hendy; A King
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132

10.  Evidence for an intrinsic renal tubular defect in mice with genetic hypophosphatemic rickets.

Authors:  L D Cowgill; S Goldfarb; K Lau; E Slatopolsky; Z S Agus
Journal:  J Clin Invest       Date:  1979-06       Impact factor: 14.808
View more
  8 in total

1.  Improved genetic mapping of X linked retinoschisis.

Authors:  N D George; S J Payne; R M Bill; D E Barton; A T Moore; J R Yates
Journal:  J Med Genet       Date:  1996-11       Impact factor: 6.318

2.  Construction of a YAC contig and an STS map spanning 3.6 megabase pairs in Xp22.1.

Authors:  D Trump; G Pilia; P H Dixon; C Wooding; R Thakrar; S E Leigh; R Nagaraja; M P Whyte; D Schlessinger; R V Thakker
Journal:  Hum Genet       Date:  1996-01       Impact factor: 4.132

Review 3.  X linked retinoschisis.

Authors:  N D George; J R Yates; A T Moore
Journal:  Br J Ophthalmol       Date:  1995-07       Impact factor: 4.638

4.  Refining the genetic map for the region flanking the X-linked hypophosphataemic rickets locus (Xp22.1-22.2).

Authors:  P S Rowe; J Goulding; A Read; H Lehrach; F Francis; A Hanauer; C Oudet; V Biancalana; S W Kooh; K E Davies
Journal:  Hum Genet       Date:  1994-03       Impact factor: 4.132

Review 5.  Regulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathway.

Authors:  Peter S N Rowe
Journal:  Crit Rev Eukaryot Gene Expr       Date:  2012       Impact factor: 1.807

Review 6.  Molecular biology of hypophosphataemic rickets and oncogenic osteomalacia.

Authors:  P S Rowe
Journal:  Hum Genet       Date:  1994-11       Impact factor: 4.132

Review 7.  The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled.

Authors:  Peter S N Rowe
Journal:  Cell Biochem Funct       Date:  2012-05-09       Impact factor: 3.685

8.  X-linked vitamin D-resistant rickets: 12 years of follow-up.

Authors:  Ahmed Anas Guerboub; Souad Moussaoui; Jad Issouani; Yassine Errahali; Ghizlaine Belmejdoub
Journal:  Pan Afr Med J       Date:  2018-05-04
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.