Literature DB >> 8096358

Linkage to markers for the chromosome region 17q12-q21 in 13 Dutch breast cancer kindreds.

P Devilee1, R S Cornelis, A Bootsma, A Bardoel, M van Vliet, I van Leeuwen, F J Cleton, A de Klein, D Lindhout, H F Vasen.   

Abstract

We have performed linkage analysis with five markers for the chromosome region 17q12-q21 in 13 Dutch breast cancer kindreds in order to find support for the claim by Hall et al. that a gene in this region, termed "BRCA1," is associated with predisposition to early-onset familial breast cancer. This work is part of a collaborative study, the results of which are published elsewhere in this issue. Best evidence for linkage was observed with the marker CMM86 (D17S74) in pedigrees with an average age at onset of < or = 47 years (LOD score = 1.77 at 1% recombination). In one breast-ovarian cancer family with a high probability of being linked to 17q, we observed one putative recombinant between D17S250 and D17S579, which suggests that BRCA1 is proximal to D17S579.

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Year:  1993        PMID： 8096358      PMCID： PMC1682089     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  30 in total

1.  Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci.

Authors:  J L Weber; A E Kwitek; P E May; M R Wallace; F S Collins; D H Ledbetter
Journal:  Nucleic Acids Res       Date:  1990-08-11       Impact factor: 16.971

2.  Loss of heterozygosity on 17p in human breast carcinomas: defining the smallest common region of deletion.

Authors:  P Devilee; C J Cornelisse; N Kuipers-Dijkshoorn; C Jonker; P L Pearson
Journal:  Cytogenet Cell Genet       Date:  1990

Review 3.  Workshop on linkage studies of hereditary breast cancer.

Authors:  G M Lenoir; S A Narod; B A Ponder
Journal:  Cancer Res       Date:  1990-07-15       Impact factor: 12.701

4.  Breast cancer in aging women. A population-based study of contrasts in stage, surgery, and survival.

Authors:  R Yancik; L G Ries; J W Yates
Journal:  Cancer       Date:  1989-03-01       Impact factor: 6.860

5.  At least four different chromosomal regions are involved in loss of heterozygosity in human breast carcinoma.

Authors:  P Devilee; M van den Broek; N Kuipers-Dijkshoorn; R Kolluri; P M Khan; P L Pearson; C J Cornelisse
Journal:  Genomics       Date:  1989-10       Impact factor: 5.736

6.  Segregation and linkage analysis of nine Utah breast cancer pedigrees.

Authors:  D T Bishop; L Cannon-Albright; T McLellan; E J Gardner; M H Skolnick
Journal:  Genet Epidemiol       Date:  1988       Impact factor: 2.135

7.  Estimating the power of linkage analysis in hereditary breast cancer.

Authors:  S A Narod; C Amos
Journal:  Am J Hum Genet       Date:  1990-02       Impact factor: 11.025

Review 8.  The search for the causes of breast and colon cancer.

Authors:  W Willett
Journal:  Nature       Date:  1989-03-30       Impact factor: 49.962

9.  Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified.

Authors:  C S Cropp; R Lidereau; G Campbell; M H Champene; R Callahan
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

Review 10.  The ninth Gordon Hamilton-Fairley memorial lecture. Hereditary cancers: clues to mechanisms of carcinogenesis.

Authors:  A G Knudson
Journal:  Br J Cancer       Date:  1989-05       Impact factor: 7.640
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  9 in total

1.  Biological indices in the assessment of breast cancer.

Authors:  A S Leong; A K Lee
Journal:  Clin Mol Pathol       Date:  1995-10

2.  Evidence for genetic anticipation in non-Mendelian diseases.

Authors:  A D Paterson; J L Kennedy; A Petronis
Journal:  Am J Hum Genet       Date:  1996-07       Impact factor: 11.025

3.  A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.

Authors:  Adam D Brown; Alison B Claybon; Alexander J R Bishop
Journal:  Mol Cell Biol       Date:  2011-06-27       Impact factor: 4.272

4.  Genetic mapping of the BRCA1 region on chromosome 17q21.

Authors:  H Albertsen; R Plaetke; L Ballard; E Fujimoto; J Connolly; E Lawrence; P Rodriguez; M Robertson; P Bradley; B Milner
Journal:  Am J Hum Genet       Date:  1994-03       Impact factor: 11.025

5.  Age at diagnosis as an indicator of eligibility for BRCA1 DNA testing in familial breast cancer.

Authors:  R S Cornelis; H F Vasen; H Meijers-Heijboer; D Ford; M van Vliet; A A van Tilborg; F J Cleton; J G Klijn; F H Menko; P Meera Khan
Journal:  Hum Genet       Date:  1995-05       Impact factor: 4.132

Review 6.  Hereditary breast cancer and family cancer syndromes.

Authors:  H T Lynch; J Lynch; T Conway; P Watson; J Feunteun; G Lenoir; S Narod; R Fitzgibbons
Journal:  World J Surg       Date:  1994 Jan-Feb       Impact factor: 3.352

7.  THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.

Authors:  A M Bowcock; L A Anderson; L S Friedman; D M Black; S Osborne-Lawrence; S E Rowell; J M Hall; E Solomon; M C King
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

8.  A radiation hybrid map of the BRCA1 region.

Authors:  P O'Connell; H Albertsen; N Matsunami; T Taylor; J E Hundley; T L Johnson-Pais; B Reus; E Lawrence; L Ballard; R White
Journal:  Am J Hum Genet       Date:  1994-03       Impact factor: 11.025

9.  Linkage analysis of BRCA1 in Japanese breast cancer families.

Authors:  R Inoue; T Fukutomi; T Ushijima; Y Matsumoto; T Sugimura; M Nagao
Journal:  Jpn J Cancer Res       Date:  1994-12
  9 in total

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