Literature DB >> 8093833

Regulation of cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase mRNA levels by L-tri-iodothyronine.

T Royo1, D Haro, F G Hegardt.   

Abstract

In hypophysectomized and thyroidectomized rats, cytosolic 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase activity, immunoreactive protein and mRNA levels were all considerably decreased. Administration of L-tri-iodothyronine (T3) resulted in a large increase in all three in hypophysectomized rats and in only a 2-fold increase (reaching the values of control rats) in thyroidectomized rats.

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Year:  1993        PMID： 8093833      PMCID： PMC1132204          DOI： 10.1042/bj2890557

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  21 in total

1.  Intracellular localization of the 3-hydroxy-3-methylglutaryl coenzme A cycle enzymes in liver. Separate cytoplasmic and mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A generating systems for cholesterogenesis and ketogenesis.

Authors:  K D Clinkenbeard; W D Reed; R A Mooney; M D Lane
Journal:  J Biol Chem       Date:  1975-04-25       Impact factor: 5.157

2.  Characterization of the different polypeptide components and analysis of subunit assembly in ferritin.

Authors:  K Ishitani; Y Niitsu; I Listowsky
Journal:  J Biol Chem       Date:  1975-04-25       Impact factor: 5.157

3.  Isolation and characterization of the nuclear matrix in Friend erythroleukemia cells: chromatin and hnRNA interactions with the nuclear matrix.

Authors:  B H Long; C Y Huang; A O Pogo
Journal:  Cell       Date:  1979-12       Impact factor: 41.582

4.  Inhibition of sterol synthesis in cultured mouse cells by cholesterol derivatives oxygenated in the side chain.

Authors:  A A Kandutsch; H W Chen
Journal:  J Biol Chem       Date:  1974-10-10       Impact factor: 5.157

5.  Diurnal rhythm of rat liver cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase.

Authors:  T Royo; J Ayté; F Albericio; E Giralt; D Haro; F G Hegardt
Journal:  Biochem J       Date:  1991-11-15       Impact factor: 3.857

6.  Molecular and catalytic properties of mitochondrial (ketogenic) 3-hydroxy-3-methylglutaryl coenzyme A synthase of liver.

Authors:  W D Reed; D Clinkenbeard; M D Lane
Journal:  J Biol Chem       Date:  1975-04-25       Impact factor: 5.157

7.  Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats.

Authors:  G C Ness; L C Pendleton; Y C Li; J Y Chiang
Journal:  Biochem Biophys Res Commun       Date:  1990-11-15       Impact factor: 3.575

8.  Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia.

Authors:  U Beisiegel; W J Schneider; M S Brown; J L Goldstein
Journal:  J Biol Chem       Date:  1982-11-10       Impact factor: 5.157

9.  Diurnal changes in the rate of cholesterogenesis in hepatocytes from fed and starved rats: effects of precursors and pancreatic hormones in vitro.

Authors:  O G Björnsson; C R Pullinger; G F Gibbons
Journal:  Arch Biochem Biophys       Date:  1985-04       Impact factor: 4.013

Review 10.  Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.

Authors:  M S Brown; J L Goldstein
Journal:  J Lipid Res       Date:  1980-07       Impact factor: 5.922
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