Literature DB >> 8083174

Genetic control of bacterial suicide: regulation of the induction of PBSX in Bacillus subtilis.

G E McDonnell1, H Wood, K M Devine, D J McConnell.   

Abstract

PBSX is a phage-like bacteriocin (phibacin) of Bacillus subtilis 168. Bacteria carrying the PBSX genome are induced by DNA-damaging agents to lyse and produce PBSX particles. The particles cannot propagate the PBSX genome. The particles produced by this suicidal response kill strains nonlysogenic for PBSX. A 5.2-kb region which controls the induction of PBSX has been sequenced. The genes identified include the previously identified repressor gene xre and a positive control factor gene, pcf. Pcf is similar to known sigma factors and acts at the late promoter PL, which has been located distal to pcf. The first two genes expressed from the late promoter show homology to genes encoding the subunits of phage terminases.

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Year:  1994        PMID： 8083174      PMCID： PMC196787          DOI： 10.1128/jb.176.18.5820-5830.1994

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  35 in total

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10.  Overproduction, isolation, and DNA-binding characteristics of Xre, the repressor protein from the Bacillus subtilis defective prophage PBSX.

Authors:  G E McDonnell; D J McConnell
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490
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