Literature DB >> 8075851

Biological actions of purines on rat megakaryocytes: potentiation by adenine of the purinoceptor-operated cytoplasmic Ca2+ oscillation.

C Uneyama1, H Uneyama, M Takahashi, N Akaike.   

Abstract

We have found that adenine enhanced the purinoceptor-operated cytoplasmic Ca2+ oscillation in rat megakaryocytes at submillimolar concentrations. Guanine and other nucleic acid bases had no effect on this system. Adenine enhanced the reaction intensity but had no effect on the threshold concentration of ATP to evoke the oscillation.

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Year:  1994        PMID： 8075851      PMCID： PMC1910359          DOI： 10.1111/j.1476-5381.1994.tb13076.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

Review 1.  Is there a basis for distinguishing two types of P2-purinoceptor?

Authors:  G Burnstock; C Kennedy
Journal:  Gen Pharmacol       Date:  1985

2.  Cytoplasmic pH regulates ATP-induced Ca(2+)-dependent K(+)-current oscillation in rat megakaryocytes.

Authors:  C Uneyama; H Uneyama; M Takahashi; N Akaike
Journal:  Biochem J       Date:  1993-10-01       Impact factor: 3.857

3.  Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.

Authors:  K Murase; P D Ryu; M Randic
Journal:  Neurosci Lett       Date:  1989-08-14       Impact factor: 3.046

4.  Differences between the effects of EDTA and citrate anticoagulants on platelet count and mean platelet volume.

Authors:  R L McShine; S Sibinga; B Brozovic
Journal:  Clin Lab Haematol       Date:  1990

5.  Cytoplasmic Ca2+ oscillation in rat megakaryocytes evoked by a novel type of purinoceptor.

Authors:  C Uneyama; H Uneyama; N Akaike
Journal:  J Physiol       Date:  1993-10       Impact factor: 5.182

6.  Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.

Authors:  N Akaike; H Uneyama; K Kawa; Y Yamashita
Journal:  Br J Pharmacol       Date:  1993-08       Impact factor: 8.739

7.  Suramin and reactive blue 2 are antagonists for a newly identified purinoceptor on rat megakaryocyte.

Authors:  H Uneyama; C Uneyama; S Ebihara; N Akaike
Journal:  Br J Pharmacol       Date:  1994-01       Impact factor: 8.739

8.  Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.

Authors:  H Uneyama; C Uneyama; N Akaike
Journal:  J Biol Chem       Date:  1993-01-05       Impact factor: 5.157

9.  Muscarinic activation of ionic currents measured by a new whole-cell recording method.

Authors:  R Horn; A Marty
Journal:  J Gen Physiol       Date:  1988-08       Impact factor: 4.086
  9 in total
  1 in total

Review 1.  Blood cells: an historical account of the roles of purinergic signalling.

Authors:  Geoffrey Burnstock
Journal:  Purinergic Signal       Date:  2015-08-11       Impact factor: 3.765
  1 in total

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