Literature DB >> 807549

Naphthyridinomycin, a new broad-spectrum antibiotic.

D Kluepfel, H A Baker, G Piattoni, S N Sehgal, A Sidorowicz, K Singh, C Vézina.   

Abstract

A new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of Streptomyces lusitanus AY B-1026. The antibiotic is active against a large number of both gram-positive and gram-negative bacteria, and inactive against Candida albicans, Trichophyton granulosum and Microsporum gypseum. The antibiotic is toxic in mice.

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Year:  1975        PMID： 807549     DOI： 10.7164/antibiotics.28.497

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

Review 1.  Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics.

Authors:  V H Le; M Inai; R M Williams; T Kan
Journal:  Nat Prod Rep       Date:  2015-02       Impact factor: 13.423

Review 2.  Natural products from thioester reductase containing biosynthetic pathways.

Authors:  Michael W Mullowney; Ryan A McClure; Matthew T Robey; Neil L Kelleher; Regan J Thomson
Journal:  Nat Prod Rep       Date:  2018-09-19       Impact factor: 13.423

Review 3.  Potent Antibiotic Lemonomycin: A Glimpse of Its Discovery, Origin, and Chemical Synthesis.

Authors:  Shunan Tao; Yang Wang; Ran Hong; Sha-Hua Huang
Journal:  Molecules       Date:  2022-07-05       Impact factor: 4.927

4.  Naphthyridinomycin, a DNA-reactive antibiotic.

Authors:  M J Zmijewski; K Miller-Hatch; M Goebel
Journal:  Antimicrob Agents Chemother       Date:  1982-05       Impact factor: 5.191

5.  The interaction of cyanonaphthyridinomycin with DNA.

Authors:  M J Zmijewski; M Mikolajczak
Journal:  Pharm Res       Date:  1985-03       Impact factor: 4.200

6.  Mechanistic studies and biological activity of bioxalomycin alpha 2, a novel antibiotic produced by Streptomyces viridodiastaticus subsp. "litoralis" LL-31F508.

Authors:  M P Singh; P J Petersen; N V Jacobus; W M Maiese; M Greenstein; D A Steinberg
Journal:  Antimicrob Agents Chemother       Date:  1994-08       Impact factor: 5.191

Review 7.  Predominately Uncultured Microbes as Sources of Bioactive Agents.

Authors:  David J Newman
Journal:  Front Microbiol       Date:  2016-11-18       Impact factor: 5.640

8.  Mining Indonesian Microbial Biodiversity for Novel Natural Compounds by a Combined Genome Mining and Molecular Networking Approach.

Authors:  Ira Handayani; Hamada Saad; Shanti Ratnakomala; Puspita Lisdiyanti; Wien Kusharyoto; Janina Krause; Andreas Kulik; Wolfgang Wohlleben; Saefuddin Aziz; Harald Gross; Athina Gavriilidou; Nadine Ziemert; Yvonne Mast
Journal:  Mar Drugs       Date:  2021-05-28       Impact factor: 5.118
  8 in total

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