Displaying radiologic images on personal computers: image processing and analysis.

This is the fourth article of our series for radiologists and imaging scientists on displaying, manipulating, and analyzing radiologic images on personal computers. Classic image processing is divided into point, area, frame, and geometric processes. Point processes change image pixel values based on the value of the pixel of interest. Histogram equalization adjusts the pixel values in the image based on the distribution of pixel values. Area processes change the pixel of interest based on the values of the surrounding pixels, known as the neighborhood. Area processes using a convolution kernel are often used as image filters. Common convolution kernels include low-frequency, high-frequency, and edge-enhancement filters. Edge enhancement can be performed with convolution kernels such as shift and difference, gradient-directional and Laplacian filters, or with nonlinear methods such as Sobel's algorithm. Frame processes mathematically combine two or more images, often for noise reduction and background subtraction. Geometric processes alter the location of pixels within the image, but usually not the pixel values. Common radiologic applications of image processing include window width and window level adjustments (point process), adaptive histogram equalization (area process), unsharp masking (area process), computed radiography image processing (combined area and point processes), digital subtraction angiography (frame and geometric processes), region of interest analysis (area process), and image rotation (geometric process). As digital imaging becomes more widespread, radiologists need to understand the image processing that is fundamental to these modalities.