Literature DB >> 8070966

Some 'difficult sequences' made easy. A study of interchain association in solid-phase peptide synthesis.

C Hyde1, T Johnson, D Owen, M Quibell, R C Sheppard.   

Abstract

Case studies of the solid-phase synthesis of some 'difficult sequences' using continuous-flow Fmoc-polyamide techniques are presented. Solvent change and peptide side chain and backbone modification procedures recently found to reduce association effects are applied, and the results compared to syntheses under standard conditions.

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Year:  1994        PMID： 8070966

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN： 0367-8377


  20 in total

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