Literature DB >> 8067767

Penicillin concentrations after increased doses of benzathine penicillin G for prevention of secondary rheumatic fever.

B J Currie1, T Burt, E L Kaplan.   

Abstract

Plasma penicillin levels were studied 2, 3, and 4 weeks after intramuscular benzathine penicillin G (BPG) doses of 1,200,000, 1,800,000, and 2,400,000 U. Proportions of patients with penicillin levels above 25 ng/ml at each week increased with increasing BPG dose. Further studies of higher-dose BPG for rheumatic fever prophylaxis are required.

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Year:  1994        PMID： 8067767      PMCID： PMC188181          DOI： 10.1128/AAC.38.5.1203

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  The role of the streptococcus in the pathogenesis of rheumatic fever.

Authors:  F J CATANZARO; C A STETSON; A J MORRIS; R CHAMOVITZ; C H RAMMELKAMP; B L STOLZER; W D PERRY
Journal:  Am J Med       Date:  1954-12       Impact factor: 4.965

2.  Prophylaxis against group A streptococcal infections in rheumatic fever patients; use of new repository penicillin preparation.

Authors:  G H STOLLERMAN; J H RUSOFF
Journal:  J Am Med Assoc       Date:  1952-12-20

3.  Penicillin for rheumatic fever prophylaxis 3-weekly or 4-weekly schedule?

Authors:  S Padmavati; V Gupta; K Prakash; K B Sharma
Journal:  J Assoc Physicians India       Date:  1987-11

4.  Pharmacokinetics of benzathine penicillin G: serum levels during the 28 days after intramuscular injection of 1,200,000 units.

Authors:  E L Kaplan; X Berrios; J Speth; T Siefferman; B Guzman; F Quesny
Journal:  J Pediatr       Date:  1989-07       Impact factor: 4.406

5.  Serum penicillin concentrations after intramuscular administration of benzathine penicillin G in children.

Authors:  C M Ginsburg; G H McCracken; T C Zweighaft
Journal:  Pediatrics       Date:  1982-04       Impact factor: 7.124

6.  Rheumatic fever recurrences: controlled study of 3-week versus 4-week benzathine penicillin prevention programs.

Authors:  H C Lue; M H Wu; K H Hsieh; G J Lin; R P Hsieh; J F Chiou
Journal:  J Pediatr       Date:  1986-02       Impact factor: 4.406
  6 in total
  7 in total

Review 1.  Prevention and treatment of rheumatic heart disease in the developing world.

Authors:  Andrew C Steer; Jonathan R Carapetis
Journal:  Nat Rev Cardiol       Date:  2009-09-15       Impact factor: 32.419

2.  A population pharmacokinetic modeling approach shows that serum penicillin G concentrations are below inhibitory concentrations by two weeks after benzathine penicillin G injection in the majority of young adults.

Authors:  Michael Neely; Edward L Kaplan; Jeffrey L Blumer; Dennis J Faix; Michael P Broderick
Journal:  Antimicrob Agents Chemother       Date:  2014-09-02       Impact factor: 5.191

3.  Four-Weekly Benzathine Penicillin G Provides Inadequate Protection against Acute Rheumatic Fever in Some Children.

Authors:  Jessica L de Dassel; Halla Malik; Anna P Ralph; Kate Hardie; Boglarka Remenyi; Joshua R Francis
Journal:  Am J Trop Med Hyg       Date:  2019-05       Impact factor: 2.345

Review 4.  Penicillin for secondary prevention of rheumatic fever.

Authors:  J Manyemba; B M Mayosi
Journal:  Cochrane Database Syst Rev       Date:  2002

5.  Serum penicillin G levels are lower than expected in adults within two weeks of administration of 1.2 million units.

Authors:  Michael P Broderick; Christian J Hansen; Kevin L Russell; Edward L Kaplan; Jeffrey L Blumer; Dennis J Faix
Journal:  PLoS One       Date:  2011-10-04       Impact factor: 3.240

6.  A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies.

Authors:  Robert M Hand; Sam Salman; Nelly Newall; Julie Vine; Madhu Page-Sharp; Asha C Bowen; Katherine Gray; Amy Baker; Joseph Kado; John Joseph; Julie Marsh; James Ramsay; Dianne Sika-Paotonu; Kevin T Batty; Laurens Manning; Jonathan Carapetis
Journal:  J Antimicrob Chemother       Date:  2019-07-01       Impact factor: 5.790

7.  One dose versus three weekly doses of benzathine penicillin G for patients co-infected with HIV and early syphilis: a multicenter, prospective observational study.

Authors:  Chia-Jui Yang; Nan-Yao Lee; Tun-Chieh Chen; Yu-Hui Lin; Shiou-Haur Liang; Po-Liang Lu; Wen-Chi Huang; Hung-Jen Tang; Chen-Hsiang Lee; Hsi-Hsun Lin; Yen-Hsu Chen; Wen-Chien Ko; Chien-Ching Hung
Journal:  PLoS One       Date:  2014-10-06       Impact factor: 3.240
  7 in total

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