Literature DB >> 8057273

Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.

A H Newman1, A C Allen, S Izenwasser, J L Katz.   

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Year:  1994        PMID: 8057273     DOI: 10.1021/jm00041a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  19 in total

1.  The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic.

Authors:  Hai-Ying Zhang; Guo-Hua Bi; Hong-Ju Yang; Yi He; Gilbert Xue; Jiajing Cao; Gianluigi Tanda; Eliot L Gardner; Amy Hauck Newman; Zheng-Xiong Xi
Journal:  Neuropsychopharmacology       Date:  2017-03-07       Impact factor: 7.853

2.  Translocation of dopamine and binding of WIN 35,428 measured under identical conditions in cells expressing the cloned human dopamine transporter.

Authors:  M E Reith; C Xu; L Zhang; L L Coffey
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996 Aug-Sep       Impact factor: 3.000

3.  Further delineation between typical and atypical dopamine uptake inhibitors: effects on food-maintained behavior and food consumption.

Authors:  Jonathan M Slezak; Rajeev I Desai; Jonathan L Katz
Journal:  Behav Pharmacol       Date:  2017-02       Impact factor: 2.293

4.  Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues.

Authors:  Jianjing Cao; Thomas E Prisinzano; Oluyomi M Okunola; Theresa Kopajtic; Matthew Shook; Jonathan L Katz; Amy Hauck Newman
Journal:  ACS Med Chem Lett       Date:  2010-10-10       Impact factor: 4.345

5.  A Medicinal Chemist's Journey at the National Institutes of Health One Molecule at a Time.

Authors:  Amy Hauck Newman
Journal:  ACS Med Chem Lett       Date:  2020-03-12       Impact factor: 4.345

6.  Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.

Authors:  Mu-Fa Zou; Jianjing Cao; Ara M Abramyan; Theresa Kopajtic; Claudio Zanettini; Daryl A Guthrie; Rana Rais; Barbara S Slusher; Lei Shi; Claus J Loland; Amy Hauck Newman
Journal:  J Med Chem       Date:  2017-12-11       Impact factor: 7.446

7.  The binding sites for benztropines and dopamine in the dopamine transporter overlap.

Authors:  Heidi Bisgaard; M Andreas B Larsen; Sonia Mazier; Thijs Beuming; Amy Hauck Newman; Harel Weinstein; Lei Shi; Claus J Loland; Ulrik Gether
Journal:  Neuropharmacology       Date:  2010-09-06       Impact factor: 5.250

8.  Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling.

Authors:  Sangeeta Raje; Jennifer Cornish; Amy H Newman; Jianjing Cao; Jonathan L Katz; Natalie D Eddington
Journal:  Pharm Res       Date:  2005-04-07       Impact factor: 4.200

9.  Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition.

Authors:  Crystal C Walline; David E Nichols; F Ivy Carroll; Eric L Barker
Journal:  J Pharmacol Exp Ther       Date:  2008-03-19       Impact factor: 4.030

Review 10.  Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction.

Authors:  Richard B Rothman; Michael H Baumann; Thomas E Prisinzano; Amy Hauck Newman
Journal:  Biochem Pharmacol       Date:  2007-08-09       Impact factor: 5.858

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