Literature DB >> 8056562

Toxic effect of intraventricular interferon-alpha in subacute sclerosing panencephalitis.

C Cianchetti1, A L Fratta, F Muntoni, G Marrosu, M G Marrosu.   

Abstract

Intraventricular interferon (IFN) administration has been shown to improve the course of SSPE. However, in 2 patients treated with intraventricular IFN-alpha-2a over a long period, we observed the appearance of clinical and EMG signs suggestive of upper and lower motor neuron pathology. These signs improved slightly in one patient after the discontinuation of IFN. It is suggested that this poly-peptide may act on specific kinds of nervous cells which selectively suffer together in various well-known neurological diseases.

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Year:  1994        PMID： 8056562     DOI： 10.1007/bf02339207

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  12 in total

1.  Persistent neurotoxicity of systemically administered interferon-alpha.

Authors:  C A Meyers; R S Scheibel; A D Forman
Journal:  Neurology       Date:  1991-05       Impact factor: 9.910

2.  Treatment of subacute sclerosing panencephalitis with alpha interferon.

Authors:  G G Gascon; S Yamani; A Cafege; L Flock; S al-Sedairy; R S Parhar; J Crowell; M Nester; I Kanaan; M A Jallu
Journal:  Ann Neurol       Date:  1991-08       Impact factor: 10.422

3.  Intraventricular interferon treatment for subacute sclerosing panencephalitis.

Authors:  I Steiner; I Wirguin; A Morag; O Abramsky
Journal:  J Child Neurol       Date:  1989-01       Impact factor: 1.987

4.  Intraventricular administration of interferon and administration of methisoprinol by mouth in the treatment of adult-onset subacute sclerosing panencephalitis.

Authors:  M G Harbord; T Jones; E P Hicks; P C Blumbergs
Journal:  Med J Aust       Date:  1988-05-02       Impact factor: 7.738

5.  Neurotoxicity of intraventricularly administered alpha-interferon for leptomeningeal disease.

Authors:  C A Meyers; E A Obbens; R S Scheibel; R P Moser
Journal:  Cancer       Date:  1991-07-01       Impact factor: 6.860

6.  The variable natural history of subacute sclerosing panencephalitis: a study of 118 cases from the Middle East.

Authors:  W S Risk; F S Haddad
Journal:  Arch Neurol       Date:  1979-10

7.  Intraventricular interferon and oral inosiplex in the treatment of subacute sclerosing panencephalitis.

Authors:  K Yalaz; B Anlar; F Oktem; S Aysun; S Ustacelebi; O Gurcay; K Gucuyener; Y Renda
Journal:  Neurology       Date:  1992-03       Impact factor: 9.910

8.  Bilateral neuralgic amyotrophy induced by interferon treatment.

Authors:  P L Bernsen; R E Wong Chung; H M Vingerhoets; J T Janssen
Journal:  Arch Neurol       Date:  1988-04

9.  Neurological effects of recombinant human interferon.

Authors:  H Smedley; M Katrak; K Sikora; T Wheeler
Journal:  Br Med J (Clin Res Ed)       Date:  1983-01-22

10.  Subacute sclerosing panencephalitis: remission after treatment with intraventricular interferon.

Authors:  H S Panitch; J Gomez-Plascencia; F H Norris; K Cantell; R A Smith
Journal:  Neurology       Date:  1986-04       Impact factor: 9.910
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  2 in total

Review 1.  Subacute sclerosing panencephalitis.

Authors:  R K Garg
Journal:  Postgrad Med J       Date:  2002-02       Impact factor: 2.401

Review 2.  Advances in Antiviral Therapy for Subacute Sclerosing Panencephalitis.

Authors:  Koichi Hashimoto; Mitsuaki Hosoya
Journal:  Molecules       Date:  2021-01-15       Impact factor: 4.411
  2 in total

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