Literature DB >> 3960334

Subacute sclerosing panencephalitis: remission after treatment with intraventricular interferon.

H S Panitch, J Gomez-Plascencia, F H Norris, K Cantell, R A Smith.   

Abstract

Three children with stage II-III subacute sclerosing panencephalitis (SSPE) were treated with intraventricular human leukocyte interferon for 6 months. All three improved to varying degrees and for different lengths of time. Clinical remissions were associated with decreased titers of antibody to measles virus in CSF and with reduced rates of intrathecal IgG synthesis. There were no serious complications or side effects. Intraventricular interferon deserves further study as a potential therapeutic agent in SSPE.

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Year:  1986        PMID： 3960334     DOI： 10.1212/wnl.36.4.562

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  13 in total

1.  CSF oligoclonal banding pattern changes in a long-surviving SSPE patient treated with alpha-IFN.

Authors:  L M Grimaldi; G V Martino
Journal:  Ital J Neurol Sci       Date:  1991-04

Review 2.  Subacute sclerosing panencephalitis.

Authors:  R K Garg
Journal:  Postgrad Med J       Date:  2002-02       Impact factor: 2.401

3.  Effective ribavirin concentration in hamster brains for antiviral chemotherapy for subacute sclerosing panencephalitis.

Authors:  T Ishii; M Hosoya; S Mori; S Shigeta; H Suzuki
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

4.  Identification of interferon-resistant subpopulations in several strains of measles virus: positive selection by growth of the virus in brain tissue.

Authors:  D R Carrigan; K K Knox
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

5.  Toxic effect of intraventricular interferon-alpha in subacute sclerosing panencephalitis.

Authors:  C Cianchetti; A L Fratta; F Muntoni; G Marrosu; M G Marrosu
Journal:  Ital J Neurol Sci       Date:  1994-04

Review 6.  Subacute sclerosing panencephalitis.

Authors:  Ravindra Kumar Garg
Journal:  J Neurol       Date:  2008-10-14       Impact factor: 4.849

Review 7.  Interferons in multiple sclerosis. A review of the evidence.

Authors:  H S Panitch
Journal:  Drugs       Date:  1992-12       Impact factor: 9.546

8.  Identification of a nonproductive, cell-associated form of measles virus by its resistance to inhibition by recombinant human interferon.

Authors:  D R Carrigan; C M Kabacoff
Journal:  J Virol       Date:  1987-06       Impact factor: 5.103

9.  IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C.

Authors:  Matthias Majer; Leonie A M Welberg; Lucile Capuron; Giuseppe Pagnoni; Charles L Raison; Andrew H Miller
Journal:  Brain Behav Immun       Date:  2008-02-06       Impact factor: 7.217

10.  Clinical conundrum: status epilepticus culminating into acute dystonia myoclonus.

Authors:  Madhuri Laxman Khilari; Praveen Kumar Sharma
Journal:  BMJ Case Rep       Date:  2020-02-28
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