| Literature DB >> 8056346 |
S Yoshimura1, H Suemizu, Y Taniguchi, K Arimori, N Kawabe, T Moriuchi.
Abstract
A genomic clone encoding the human plasma glutathione peroxidase (PGPx), a major enzyme in reducing lipid hydroperoxide and hydrogen peroxide in plasma, was isolated and 5618 nucleotides (nt) were determined. The nt sequence data revealed that the PGPx gene is composed of five exons spanning approx. 10 kb. Primer extension experiments mapped the transcription start point at 298 nt upstream from the predicted start codon. Twenty nt upstream from the polyadenylation site of the gene, an uncanonical polyadenylation signal, AGTAAA, was found. Human PGPx was localized on chromosome 5 band q32 by fluorescence in situ hybridization.Entities:
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Year: 1994 PMID： 8056346 DOI： 10.1016/0378-1119(94)90023-x
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688