Literature DB >> 8055713

DNA amplification: new insights into its mechanism.

E Wintersberger1.   

Abstract

DNA amplification is a process whereby a limited part of the genome is increased in copy number with various consequences for the cell. It is frequently observed in cancer cells and it can be induced in mammalian cells grown in culture as well as in tumor cells when these are subjected to growth inhibiting drugs. In recent years new insights into the mechanisms involved in DNA amplification have been obtained; discussion of these will form the major subject of this short review.

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Year:  1994        PMID： 8055713     DOI： 10.1007/bf00352315

Source DB:  PubMed          Journal:  Chromosoma        ISSN： 0009-5915            Impact factor:   4.316


  90 in total

1.  DNA amplification is rare in normal human cells.

Authors:  J A Wright; H S Smith; F M Watt; M C Hancock; D L Hudson; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

2.  Loss of telomeric DNA during aging may predispose cells to cancer (review).

Authors:  J Shay; W Wright; H Werbin
Journal:  Int J Oncol       Date:  1993-10       Impact factor: 5.650

3.  Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.

Authors:  D D Von Hoff; D R Needham-VanDevanter; J Yucel; B E Windle; G M Wahl
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

4.  Association of fragile X syndrome with delayed replication of the FMR1 gene.

Authors:  R S Hansen; T K Canfield; M M Lamb; S M Gartler; C D Laird
Journal:  Cell       Date:  1993-07-02       Impact factor: 41.582

5.  Correlations between sister chromatid exchange frequencies and replicon sizes. A model for the mechanism of SCE production.

Authors:  J E Cleaver
Journal:  Exp Cell Res       Date:  1981-11       Impact factor: 3.905

Review 6.  The p53 tumour suppressor gene.

Authors:  A J Levine; J Momand; C A Finlay
Journal:  Nature       Date:  1991-06-06       Impact factor: 49.962

7.  Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.

Authors:  Y Xiong; H Zhang; D Beach
Journal:  Genes Dev       Date:  1993-08       Impact factor: 11.361

Review 8.  Common and unique features of T antigens encoded by the polyomavirus group.

Authors:  J M Pipas
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

9.  Cyclin A is required for the onset of DNA replication in mammalian fibroblasts.

Authors:  F Girard; U Strausfeld; A Fernandez; N J Lamb
Journal:  Cell       Date:  1991-12-20       Impact factor: 41.582

10.  Cyclin A is required at two points in the human cell cycle.

Authors:  M Pagano; R Pepperkok; F Verde; W Ansorge; G Draetta
Journal:  EMBO J       Date:  1992-03       Impact factor: 11.598
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  3 in total

1.  Evidence for a megareplicon covering megabases of centromeric chromosome segments.

Authors:  G Holló; J Keresö; T Praznovszky; I Cserpán; K Fodor; R Katona; E Csonka; K Fátyol; A Szeles; A A Szalay; G Hadlaczky
Journal:  Chromosome Res       Date:  1996-04       Impact factor: 5.239

2.  Genetic alterations in hormone-refractory recurrent prostate carcinomas.

Authors:  N N Nupponen; L Kakkola; P Koivisto; T Visakorpi
Journal:  Am J Pathol       Date:  1998-07       Impact factor: 4.307

3.  Cytomolecular characterization of de novo formed rye B chromosome variants.

Authors:  André Marques; Sonja Klemme; Marcelo Guerra; Andreas Houben
Journal:  Mol Cytogenet       Date:  2012-07-16       Impact factor: 2.009
  3 in total

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