Literature DB >> 8052620

Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas.

J Weaver-Feldhaus1, N A Gruis, S Neuhausen, D Le Paslier, E Stockert, M H Skolnick, A Kamb.   

Abstract

The p21 region of human chromosome 9 is thought to contain a gene (MLM) involved in genetic susceptibility to melanoma and a gene or genes that influence progression of certain other tumors. Genomic clones that span a large region in 9p21 surrounding the presumptive tumor suppressor gene(s) have been isolated. A set of sequence-tagged sites in this region has been developed. By using these markers and others previously reported, the 9p21 region has been studied by physical mapping in 84 melanoma cell lines. A putative tumor suppressor gene, perhaps MLM itself, has been localized to a region of less than 40 kb that lies proximal (centromeric) to the alpha-interferon gene cluster.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8052620      PMCID： PMC44442          DOI： 10.1073/pnas.91.16.7563

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  14 in total

1.  Dinucleotide repeat polymorphism at the IFNA locus (9p22).

Authors:  D J Kwiatkowski; M O Diaz
Journal:  Hum Mol Genet       Date:  1992-11       Impact factor: 6.150

2.  A rapid alkaline extraction procedure for screening recombinant plasmid DNA.

Authors:  H C Birnboim; J Doly
Journal:  Nucleic Acids Res       Date:  1979-11-24       Impact factor: 16.971

3.  A first-generation physical map of the human genome.

Authors:  D Cohen; I Chumakov; J Weissenbach
Journal:  Nature       Date:  1993-12-16       Impact factor: 49.962

4.  Cytogenetics of non-small cell lung cancer: analysis of consistent non-random abnormalities.

Authors:  R Lukeis; L Irving; M Garson; S Hasthorpe
Journal:  Genes Chromosomes Cancer       Date:  1990-07       Impact factor: 5.006

5.  Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.

Authors:  O I Olopade; D L Buchhagen; K Malik; J Sherman; T Nobori; S Bader; M M Nau; A F Gazdar; J D Minna; M O Diaz
Journal:  Cancer Res       Date:  1993-05-15       Impact factor: 12.701

6.  Confirmation of chromosome 9p linkage in familial melanoma.

Authors:  D J Nancarrow; G J Mann; E A Holland; G J Walker; S C Beaton; M K Walters; C Luxford; J M Palmer; J A Donald; J L Weber
Journal:  Am J Hum Genet       Date:  1993-10       Impact factor: 11.025

7.  Linkage analysis in Dutch familial atypical multiple mole-melanoma (FAMMM) syndrome families. Effect of naevus count.

Authors:  N A Gruis; L A Sandkuijl; J L Weber; A van der Zee; A M Borgstein; W Bergman; R R Frants
Journal:  Melanoma Res       Date:  1993-08       Impact factor: 3.599

8.  Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22.

Authors:  L A Cannon-Albright; D E Goldgar; L J Meyer; C M Lewis; D E Anderson; J W Fountain; M E Hegi; R W Wiseman; E M Petty; A E Bale
Journal:  Science       Date:  1992-11-13       Impact factor: 47.728

Review 9.  Human melanocytic neoplasms and their etiologic relationship with sunlight.

Authors:  D E Elder
Journal:  J Invest Dermatol       Date:  1989-05       Impact factor: 8.551

10.  Systemic cancer and the FAMMM syndrome.

Authors:  W Bergman; P Watson; J de Jong; H T Lynch; R M Fusaro
Journal:  Br J Cancer       Date:  1990-06       Impact factor: 7.640
View more
  9 in total

1.  Recessive oncogenes: current status.

Authors:  Xiang Gao; Kenneth V Honn
Journal:  Pathol Oncol Res       Date:  1995       Impact factor: 3.201

2.  Molecular differential diagnosis of renal cell carcinomas by microsatellite analysis.

Authors:  P Bugert; G Kovacs
Journal:  Am J Pathol       Date:  1996-12       Impact factor: 4.307

3.  Discovering tumor suppressor genes through genome-wide copy number analysis.

Authors:  S Michael Rothenberg; Jeff Settleman
Journal:  Curr Genomics       Date:  2010-08       Impact factor: 2.236

4.  Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21.

Authors:  O I Olopade; H M Pomykala; F Hagos; L W Sveen; R Espinosa; M H Dreyling; S Gursky; W M Stadler; M M Le Beau; S K Bohlander
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-03       Impact factor: 11.205

5.  Chromosome 9p deletions in cutaneous malignant melanoma tumors: the minimal deleted region involves markers outside the p16 (CDKN2) gene.

Authors:  S Puig; A Ruiz; C Lázaro; T Castel; M Lynch; J Palou; A Vilalta; J Weissenbach; J M Mascaro; X Estivill
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

Review 6.  Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.

Authors:  C Cordon-Cardo
Journal:  Am J Pathol       Date:  1995-09       Impact factor: 4.307

Review 7.  Targeting NADPH oxidases for the treatment of cancer and inflammation.

Authors:  Michael Y Bonner; Jack L Arbiser
Journal:  Cell Mol Life Sci       Date:  2012-05-13       Impact factor: 9.261

8.  Loss of heterozygosity analysis of keratoacanthoma reveals multiple differences from cutaneous squamous cell carcinoma.

Authors:  A J Waring; M Takata; I Rehman; J L Rees
Journal:  Br J Cancer       Date:  1996-03       Impact factor: 7.640

9.  Frequent loss of the cyclin-dependent kinase-4 inhibitor gene in human gliomas.

Authors:  A Gomi; R Sakai; S Ogawa; S Shinoda; H Hirai; T Masuzawa
Journal:  Jpn J Cancer Res       Date:  1995-04
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.