| Literature DB >> 8050572 |
V D Mehta1, P V Kulkarni, R P Mason, A Constantinescu, S Aravind, N Goomer, P P Antich.
Abstract
6-Fluoropyridoxol was evaluated as an intracellular pH indicator. This molecule exhibits exceptional sensitivity to changes in pH (approximately 10 ppm acid/base shift) and a pKa approximately 8.2 appropriate for physiological investigations. Using 19F NMR spectroscopy we determined both intra- and extracellular pH in whole blood and confirmed the measurements using traditional techniques: ion-electrodes and 31P NMR spectroscopy.Entities:
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Year: 1994 PMID： 8050572 DOI： 10.1016/0014-5793(94)00675-x
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124