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Literature DB >> 8045571

Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels.

A Zingone¹, A Dominijanni, E Mele, O Marasco, F Melina, P Minchella, B Quaresima, M T Tiano, A Gnasso, A Pujia.

Abstract

The frequency and distribution of angiotensin converting enzyme insertion/deletion (ACE I/D) polymorphism, and its association with other known risk factors for coronary atherosclerosis, has been studied, in a normal south Italian population. Subjects homozygous for deletion showed elevated fasting blood glucose levels when compared with subjects homozygous for insertion. The difference was consistent with an increased number of type 2 diabetics among the former group of subjects.

Entities: Chemical Disease Gene

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Year: 1994 PMID： 8045571 DOI： 10.1007/bf00202873

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

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