Literature DB >> 8040073

FL-120A-D', new products related to kinamycin from Streptomyces chattanoogensis subsp. taitungensis subsp. nov. II. Isolation and structure determination.

J J Young1, S N Ho, W M Ju, L R Chang.   

Abstract

Six new kinamycin antibiotics have been isolated from the culture filtrate of Streptomyces chattanoogensis. The structures of six related components were determined employing 1D and 2D NMR spectroscopy and mass spectrometry. These structures represent the first reported epoxide kinamycin (2, 3) and propionyl derivative of kinamycin (5), and new isobutyryl derivatives of kinamycin (1, 4, 6).

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Year:  1994        PMID: 8040073     DOI: 10.7164/antibiotics.47.681

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  5 in total

1.  Asymmetric total synthesis of the epoxykinamycin FL-120 B'.

Authors:  Stephen S Scully; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2011-08-30       Impact factor: 15.336

Review 2.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors:  Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal:  Chem Rev       Date:  2017-04-04       Impact factor: 60.622

3.  Development of enantioselective synthetic routes to (-)-kinamycin F and (-)-lomaiviticin aglycon.

Authors:  Christina M Woo; Shivajirao L Gholap; Liang Lu; Miho Kaneko; Zhenwu Li; P C Ravikumar; Seth B Herzon
Journal:  J Am Chem Soc       Date:  2012-10-03       Impact factor: 15.419

4.  Studies toward the synthesis of the epoxykinamycin FL-120B': discovery of a decarbonylative photocyclization.

Authors:  Stephen S Scully; John A Porco
Journal:  Org Lett       Date:  2012-05-09       Impact factor: 6.005

5.  Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis.

Authors:  Bin Wang; Fang Guo; Jinwei Ren; Guomin Ai; Bertrand Aigle; Keqiang Fan; Keqian Yang
Journal:  Nat Commun       Date:  2015-07-02       Impact factor: 14.919

  5 in total

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