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Literature DB >> 21953671

Asymmetric total synthesis of the epoxykinamycin FL-120 B'.

Stephen S Scully¹, John A Porco.

Abstract

Entities: Chemical Disease Gene Mutation

Mesh：

Substances：

Year: 2011 PMID： 21953671 PMCID： PMC3477604 DOI： 10.1002/anie.201104504

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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33 in total

1. Atroposelective synthesis of axially chiral biaryl compounds.

Authors: Gerhard Bringmann; Anne J Price Mortimer; Paul A Keller; Mary J Gresser; James Garner; Matthias Breuning
Journal: Angew Chem Int Ed Engl Date: 2005-08-26 Impact factor: 15.336

2. Total synthesis of kinamycins C, F, and J.

Authors: K C Nicolaou; Hongming Li; Andrea L Nold; Doron Pappo; Achim Lenzen
Journal: J Am Chem Soc Date: 2007-08-04 Impact factor: 15.419

3. 11-Step enantioselective synthesis of (-)-lomaiviticin aglycon.

Authors: Seth B Herzon; Liang Lu; Christina M Woo; Shivajirao L Gholap
Journal: J Am Chem Soc Date: 2011-01-31 Impact factor: 15.419

4. Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event.

Authors: Hong Geun Lee; Jae Young Ahn; Amy S Lee; Matthew D Shair
Journal: Chemistry Date: 2010-11-22 Impact factor: 5.236

5. Structures and biological properties of Kinamycin A, B, C, and D.

Authors: S Omura; A Nakagawa; H Yamada; T Hata; A Furusaki
Journal: Chem Pharm Bull (Tokyo) Date: 1973-05 Impact factor: 1.645

6. A new antibiotic, kinamycin.

Authors: S Itŏ; T Matsuya; S Omura; M Otani; A Nakagawa
Journal: J Antibiot (Tokyo) Date: 1970-06 Impact factor: 2.649

7. Total synthesis of the quinone epoxide dimer (+)-torreyanic acid: application of a biomimetic oxidation/electrocyclization/Diels-Alder dimerization cascade.

Authors: Chaomin Li; Richard P Johnson; John A Porco
Journal: J Am Chem Soc Date: 2003-04-30 Impact factor: 15.419

8. Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.

Authors: Kimberley A O'Hara; Xing Wu; Daywin Patel; Hong Liang; Jack C Yalowich; Nan Chen; Valerie Goodfellow; Otunola Adedayo; Gary I Dmitrienko; Brian B Hasinoff
Journal: Free Radic Biol Med Date: 2007-07-13 Impact factor: 7.376

9. New products related to kinamycin from Streptomyces murayamaensis. I. Taxonomy, production, isolation and biological properties.

Authors: M C Cone; P J Seaton; K A Halley; S J Gould
Journal: J Antibiot (Tokyo) Date: 1989-02 Impact factor: 2.649

Asymmetric total synthesis of the epoxykinamycin FL-120 B'.

1. Atroposelective synthesis of axially chiral biaryl compounds.

2. Total synthesis of kinamycins C, F, and J.

3. 11-Step enantioselective synthesis of (-)-lomaiviticin aglycon.

4. Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event.

5. Structures and biological properties of Kinamycin A, B, C, and D.

6. A new antibiotic, kinamycin.

7. Total synthesis of the quinone epoxide dimer (+)-torreyanic acid: application of a biomimetic oxidation/electrocyclization/Diels-Alder dimerization cascade.

8. Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.

9. New products related to kinamycin from Streptomyces murayamaensis. I. Taxonomy, production, isolation and biological properties.

10. Stereocontrolled assembly of the C3/C3' dideoxy core of lomaiviticin A/B and congeners.

1. Multigram Synthesis of 1-O-Acetyl-3-O-(4-methoxybenzyl)-4-N-(9-fluorenylmethoxycarbonyl)-4-N-methyl-L-pyrrolosamine.

2. Stereocontrolled Synthesis of the Fully Glycosylated Monomeric Unit of Lomaiviticin A.

Review 3. Applications of Friedel-Crafts reactions in total synthesis of natural products.

4. Development of enantioselective synthetic routes to (-)-kinamycin F and (-)-lomaiviticin aglycon.

5. Studies toward the synthesis of the epoxykinamycin FL-120B': discovery of a decarbonylative photocyclization.

6. Structure Revision of the Lomaiviticins.

7. Synthesis of the bis(cyclohexenone) core of (-)-lomaiviticin A.