Literature DB >> 8039477

Tiagabine.

H Mengel1.   

Abstract

Tiagabine (TGB), a specific gamma-aminobutyric acid (GABA)-uptake inhibitor, is a potential new antiepileptic drug with a novel mechanism of action. In animal models of epilepsy as well as in a placebo-controlled trial in patients with complex partial seizures, TGB showed significant anticonvulsant effects. TGB was well tolerated by most patients.

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Year:  1994        PMID： 8039477     DOI： 10.1111/j.1528-1157.1994.tb05976.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN： 0013-9580            Impact factor:   5.864


  4 in total

Review 1.  Management of focal-onset seizures: an update on drug treatment.

Authors:  Svein I Johannessen; Elinor Ben-Menachem
Journal:  Drugs       Date:  2006       Impact factor: 9.546

2.  Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans.

Authors:  K J Werhahn; E Kunesch; S Noachtar; R Benecke; J Classen
Journal:  J Physiol       Date:  1999-06-01       Impact factor: 5.182

Review 3.  Management of epilepsy in women of childbearing age: practical recommendations.

Authors:  Barbara Tettenborn
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

4.  Seizures in a pediatric patient with a tiagabine overdose.

Authors:  Ziad N Kazzi; Chris C Jones; Brent W Morgan
Journal:  J Med Toxicol       Date:  2006-12
  4 in total

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