PURPOSE: To determine the accuracy and reliability of magnetic resonance (MR) angiography for identification of stenosis and patent distal vessels in patients with peripheral vascular disease. MATERIALS AND METHODS: Two-dimensional time-of-flight MR angiography and conventional arteriography were performed in 22 patients. Four blinded radiologists independently graded multiple anatomic segments. RESULTS: MR angiography allowed detection of more patent vessel segments than did conventional arteriography. For detection of significant stenosis (> 75%), MR angiography had 43%-67% sensitivity and 74%-89% specificity. Discrepancies in detection of significant stenosis occurred in 39 segments for the most accurate reviewer; 27 of these discrepancies were avoidable. CONCLUSION: For detection of significant stenosis, MR angiography has low to moderate sensitivity and specificity; however, observer variability appears to be a major contributing factor to the discrepancies. Greater reviewer experience or techniques for improving reliability may improve the accuracy of MR angiography in peripheral vascular disease.
PURPOSE: To determine the accuracy and reliability of magnetic resonance (MR) angiography for identification of stenosis and patent distal vessels in patients with peripheral vascular disease. MATERIALS AND METHODS: Two-dimensional time-of-flight MR angiography and conventional arteriography were performed in 22 patients. Four blinded radiologists independently graded multiple anatomic segments. RESULTS: MR angiography allowed detection of more patent vessel segments than did conventional arteriography. For detection of significant stenosis (> 75%), MR angiography had 43%-67% sensitivity and 74%-89% specificity. Discrepancies in detection of significant stenosis occurred in 39 segments for the most accurate reviewer; 27 of these discrepancies were avoidable. CONCLUSION: For detection of significant stenosis, MR angiography has low to moderate sensitivity and specificity; however, observer variability appears to be a major contributing factor to the discrepancies. Greater reviewer experience or techniques for improving reliability may improve the accuracy of MR angiography in peripheral vascular disease.
Authors: Ioannis Koktzoglou; Charles A Mistretta; Shivraman Giri; Eugene E Dunkle; Parag Amin; Robert R Edelman Journal: Magn Reson Med Date: 2013-11-11 Impact factor: 4.668
Authors: Robert R Edelman; John J Sheehan; Eugene Dunkle; Nancy Schindler; James Carr; Ioannis Koktzoglou Journal: Magn Reson Med Date: 2010-04 Impact factor: 4.668
Authors: Annette Hentsch; Manuela A Aschauer; Jörn O Balzer; Joachim Brossmann; Hans P Busch; Kirsten Davis; Philippe Douek; Franz Ebner; Jos M A van Engelshoven; Michaela Gregor; Christian Kersting; Patrick R Knüsel; Edward Leen; Tim Leiner; Christian Loewe; Simon McPherson; Peter Reimer; Fritz K W Schäfer; Matthias Taupitz; Siegfried A Thurnher; Bernd Tombach; Robin Wegener; Dominik Weishaupt; James F M Meaney Journal: Eur Radiol Date: 2003-03-25 Impact factor: 5.315