Literature DB >> 8026088

Head and neck carcinoma--stage at presentation.

G A Vernham1, J A Crowther.   

Abstract

A prospective study was performed during a 2-year-period. A total of 127 patients presenting with a squamous cell carcinoma of the head, neck and upper aerodigestive tract were entered into the study. Patients were classified according to the primary site, namely: larynx (n = 44), oropharynx (n = 28), hypopharynx (n = 17) and oral cavity (n = 19) and others (n = 19). Patients were staged according to the UICC TNM classification (1987) and the nature and duration of their symptoms were recorded. Sixty-one per cent of patients were found to be presenting with advanced disease (stages 3 and 4): oropharynx--71%; hypopharynx--77%; oral cavity--50%; larynx--34%. No relationship could be established between stage at presentation and duration of symptoms and 53% of patients with advanced disease had been symptomatic for less than 3 months at the time of diagnosis. Only 28% of patients presenting with stage 3 or 4 disease had symptoms for 3 months or longer. Earlier diagnosis will not make a significant impact on the overall prognosis in head and neck cancer.

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Year:  1994        PMID: 8026088     DOI: 10.1111/j.1365-2273.1994.tb01194.x

Source DB:  PubMed          Journal:  Clin Otolaryngol Allied Sci        ISSN: 0307-7772


  12 in total

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Review 8.  Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma--a systematic review.

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9.  Decitabine rescues cisplatin resistance in head and neck squamous cell carcinoma.

Authors:  Chi T Viet; Dongmin Dang; Stacy Achdjian; Yi Ye; Samuel G Katz; Brian L Schmidt
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10.  The luminance ratio of autofluorescence in a xenograft mouse model is stable through tumor growth stages.

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