Literature DB >> 8021810

A shape factor to characterize the quality of spheroids.

F Podczeck1, J M Newton.   

Abstract

A shape factor eR has been devised to describe how the form of spherical particles approaches that of a true spheroid, based on a two-dimensional image analysis. Both the deviation of shape from a circle towards an ellipse and surface irregularities influence the value of eR. Using a set of model figures such as squares, triangles, diamonds and stars, it could be shown that eR clearly differentiates between different polygonally symmetric figures, even in the case where common shape descriptors such as the aspect ratio provide equal values. The value of eR is 1.0 in the case of a perfect spheroid, while ellipticity and surface roughness lead to a significant change in the value.

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Year:  1994        PMID: 8021810     DOI: 10.1111/j.2042-7158.1994.tb03745.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  8 in total

1.  The influence of surfactant HLB and oil/surfactant ratio on the formation and properties of self-emulsifying pellets and microemulsion reconstitution.

Authors:  Irini Matsaridou; Panagiotis Barmpalexis; Andrea Salis; Ioannis Nikolakakis
Journal:  AAPS PharmSciTech       Date:  2012-09-28       Impact factor: 3.246

2.  Relationships between the properties of self-emulsifying pellets and of the emulsions used as massing liquids for their preparation.

Authors:  Ioannis Nikolakakis; Athanasia Panagopoulou; Andrea Salis; Stavros Malamataris
Journal:  AAPS PharmSciTech       Date:  2014-09-12       Impact factor: 3.246

3.  Functionality of cross-linked polyvinylpyrrolidone as a spheronization aid: a promising alternative to microcrystalline cellulose.

Authors:  Celine V Liew; Li Gu; Josephine L P Soh; Paul W S Heng
Journal:  Pharm Res       Date:  2005-08-03       Impact factor: 4.200

4.  Automatic detection of carotid arteries in computed tomography angiography: a proof of concept protocol.

Authors:  Florentino Luciano Caetano Dos Santos; Atte Joutsen; Michelangelo Paci; Juha Salenius; Hannu Eskola
Journal:  Int J Cardiovasc Imaging       Date:  2016-05-03       Impact factor: 2.357

5.  Isolated pancreatic islet yield and quality is inversely related to organ donor age in rats.

Authors:  Nelson Gonzalez; Mayra Salgado; Leonard Medrano; Yoko Mullen; Hirotake Komatsu
Journal:  Exp Gerontol       Date:  2019-10-18       Impact factor: 4.253

Review 6.  Self-Emulsifying Granules and Pellets: Composition and Formation Mechanisms for Instant or Controlled Release.

Authors:  Ioannis Nikolakakis; Ioannis Partheniadis
Journal:  Pharmaceutics       Date:  2017-11-03       Impact factor: 6.321

7.  Effect of lipid and cellulose based matrix former on the release of highly soluble drug from extruded/spheronized, sintered and compacted pellets.

Authors:  Madiha Maboos; Rabia Ismail Yousuf; Muhammad Harris Shoaib; Iqbal Nasiri; Tazeen Hussain; Hafiza Fouzia Ahmed; Wajiha Iffat
Journal:  Lipids Health Dis       Date:  2018-06-09       Impact factor: 3.876

8.  A Multiparametric Assessment of Human Islets Predicts Transplant Outcomes in Diabetic Mice.

Authors:  Hirotake Komatsu; Meirigeng Qi; Nelson Gonzalez; Mayra Salgado; Leonard Medrano; Jeffrey Rawson; Chris Orr; Keiko Omori; Jeffrey S Isenberg; Fouad Kandeel; Yoko Mullen; Ismail H Al-Abdullah
Journal:  Cell Transplant       Date:  2021 Jan-Dec       Impact factor: 4.064

  8 in total

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