Literature DB >> 8012549

Separation of picrocrocin, cis-trans-crocins and safranal of saffron using high-performance liquid chromatography with photodiode-array detection.

P A Tarantilis1, M Polissiou, M Manfait.   

Abstract

High-performance liquid chromatography with photodiode-array detection was used to separate picrocrocin (bitter-tasting component, glucoside of safranal), cis/trans-crocins (carotenoids, glucosyl esters of crocetin) and safranal (flavour, monoterpene aldehyde) of saffron. All components of pure red Greek saffron were extracted from dried stigma with 50% methanol. These compounds were detected, separated collected and identified simultaneously using a Merck LiChroCART 125-4 Superspher 100 RP-18 (4 microns) column and as mobile phase a linear gradient from 20% to 100% acetonitrile in water in 20 min with a detection wavelength at 308 nm.

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Year:  1994        PMID: 8012549     DOI: 10.1016/0021-9673(94)80628-4

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  10 in total

1.  Molecular basis of protective effect by crocetin on survival and liver tissue damage following hemorrhagic shock.

Authors:  Animesh Dhar; George Cherian; Gopal Dhar; Gibanananda Ray; Ram Sharma; Sushanta K Banerjee
Journal:  Mol Cell Biochem       Date:  2005-10       Impact factor: 3.396

2.  Effective Isolation of Picrocrocin and Crocins from Saffron: From HPTLC to Working Standard Obtaining.

Authors:  Laurynas Jarukas; Konradas Vitkevicius; Olha Mykhailenko; Ivan Bezruk; Victoriya Georgiyants; Liudas Ivanauskas
Journal:  Molecules       Date:  2022-07-03       Impact factor: 4.927

3.  Cytosolic and plastoglobule-targeted carotenoid dioxygenases from Crocus sativus are both involved in beta-ionone release.

Authors:  Angela Rubio; José Luís Rambla; Marcella Santaella; M Dolores Gómez; Diego Orzaez; Antonio Granell; Lourdes Gómez-Gómez
Journal:  J Biol Chem       Date:  2008-07-07       Impact factor: 5.157

4.  Molecular species fingerprinting and quantitative analysis of saffron (Crocus sativus L.) for quality control by MALDI mass spectrometry.

Authors:  Donatella Aiello; Carlo Siciliano; Fabio Mazzotti; Leonardo Di Donna; Constantinos M Athanassopoulos; Anna Napoli
Journal:  RSC Adv       Date:  2018-10-23       Impact factor: 4.036

5.  Rapid determination of volatile constituents in safflower from Xinjiang and Henan by ultrasonic-assisted solvent extraction and GC-MS.

Authors:  Ling-Han Jia; Yi Liu; Yu-Zhen Li
Journal:  J Pharm Anal       Date:  2011-07-22

Review 6.  Medicinally important aromatic plants with radioprotective activity.

Authors:  Ravindra M Samarth; Meenakshi Samarth; Yoshihisa Matsumoto
Journal:  Future Sci OA       Date:  2017-09-21

Review 7.  Crocus sativus L. Extracts and Its Constituents Crocins and Safranal; Potential Candidates for Schizophrenia Treatment?

Authors:  Nikolaos Pitsikas
Journal:  Molecules       Date:  2021-02-25       Impact factor: 4.411

8.  Molecular Mechanisms behind Safranal's Toxicity to HepG2 Cells from Dual Omics.

Authors:  David Roy Nelson; Ala'a Al Hrout; Amnah Salem Alzahmi; Amphun Chaiboonchoe; Amr Amin; Kourosh Salehi-Ashtiani
Journal:  Antioxidants (Basel)       Date:  2022-06-07

9.  Evaluation of therapeutic effects of crocin in attenuating the progression of diabetic nephropathy: a preliminary randomized triple-blind placebo-controlled trial.

Authors:  Asma Jaafarinia; Behzad Kafami; Adeleh Sahebnasagh; Fatemeh Saghafi
Journal:  BMC Complement Med Ther       Date:  2022-10-08

10.  Safranal: from an aromatic natural product to a rewarding pharmacological agent.

Authors:  Ramin Rezaee; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

  10 in total

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