PURPOSE: To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age. METHODS: MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions. RESULTS: There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age. CONCLUSION: In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life.
PURPOSE: To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age. METHODS: MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions. RESULTS: There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age. CONCLUSION: In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life.
Authors: O C Okonkwo; G Xu; N M Dowling; B B Bendlin; A Larue; B P Hermann; R Koscik; E Jonaitis; H A Rowley; C M Carlsson; S Asthana; M A Sager; S C Johnson Journal: Neurology Date: 2012-05-16 Impact factor: 9.910
Authors: Angela L Jefferson; Jayandra J Himali; Rhoda Au; Sudha Seshadri; Charles Decarli; Christopher J O'Donnell; Philip A Wolf; Warren J Manning; Alexa S Beiser; Emelia J Benjamin Journal: Am J Cardiol Date: 2011-08-30 Impact factor: 2.778
Authors: Angela L Jefferson; Jayandra J Himali; Alexa S Beiser; Rhoda Au; Joseph M Massaro; Sudha Seshadri; Philimon Gona; Carol J Salton; Charles DeCarli; Christopher J O'Donnell; Emelia J Benjamin; Philip A Wolf; Warren J Manning Journal: Circulation Date: 2010-08-02 Impact factor: 29.690
Authors: Giovanni B Frisoni; Cristina Geroldi; Alberto Beltramello; Angelo Bianchetti; Giuliano Binetti; Giovanni Bordiga; Charles DeCarli; Mikko P Laakso; Hilkka Soininen; Cristina Testa; Orazio Zanetti; Marco Trabucchi Journal: AJNR Am J Neuroradiol Date: 2002-01 Impact factor: 3.825
Authors: Yulin Ge; Robert I Grossman; James S Babb; Marcie L Rabin; Lois J Mannon; Dennis L Kolson Journal: AJNR Am J Neuroradiol Date: 2002-09 Impact factor: 3.825