Literature DB >> 7990105

A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist.

P K Chakravarty1, E M Naylor, A Chen, R S Chang, T B Chen, K A Faust, V J Lotti, S D Kivlighn, R A Gable, G J Zingaro.   

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Year:  1994        PMID： 7990105     DOI： 10.1021/jm00050a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  4 in total

1.  Acylsulfonamide-Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH.

Authors:  Tsukasa Mizuhara; Krishnendu Saha; Daniel F Moyano; Chang Soo Kim; Bo Yan; Young-Kwan Kim; Vincent M Rotello
Journal:  Angew Chem Int Ed Engl       Date:  2015-04-14       Impact factor: 15.336

2.  Development of an in vivo active, dual EP1 and EP3 selective antagonist based on a novel acyl sulfonamide bioisostere.

Authors:  Jason D Downey; Sam A Saleh; Thomas M Bridges; Ryan D Morrison; J Scott Daniels; Craig W Lindsley; Richard M Breyer
Journal:  Bioorg Med Chem Lett       Date:  2012-11-24       Impact factor: 2.823

3.  Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli.

Authors:  Veronica Berg; Pralay Das; Erik Chorell; Mattias Hedenström; Jerome S Pinkner; Scott J Hultgren; Fredrik Almqvist
Journal:  Bioorg Med Chem Lett       Date:  2008-05-07       Impact factor: 2.823

4.  Design, Synthesis and Fungicidal Activity of 2-Substituted Phenyl-2-oxo-, 2-Hydroxy- and 2-Acyloxyethylsulfonamides.

Authors:  Minlong Wang; Peng Rui; Caixiu Liu; Ying Du; Peiwen Qin; Zhiqiu Qi; Mingshan Ji; Xinghai Li; Zining Cui
Journal:  Molecules       Date:  2017-05-04       Impact factor: 4.411
  4 in total

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