Literature DB >> 7988658

Hsp70 in mitochondrial biogenesis: from chaperoning nascent polypeptide chains to facilitation of protein degradation.

R A Stuart1, D M Cyr, W Neupert.   

Abstract

The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology. Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non-native conformations at distinct stages during their life in the cell. In this paper we review work pertaining to the functions of hsp70 proteins in chaperoning mitochondrial protein biogenesis. Hsp70 proteins function in protein synthesis, proteins to proteolytic enzymes in the mitochondrial matrix.

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Year:  1994        PMID： 7988658     DOI： 10.1007/BF01923454

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  53 in total

1.  Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis.

Authors:  J Ostermann; A L Horwich; W Neupert; F U Hartl
Journal:  Nature       Date:  1989-09-14       Impact factor: 49.962

2.  Transport of proteins into mitochondria: translocational intermediates spanning contact sites between outer and inner membranes.

Authors:  M Schleyer; W Neupert
Journal:  Cell       Date:  1985-11       Impact factor: 41.582

3.  A matrix ATP requirement for presequence translocation across the inner membrane of mitochondria.

Authors:  D M Cyr; R A Stuart; W Neupert
Journal:  J Biol Chem       Date:  1993-11-15       Impact factor: 5.157

Review 4.  Mitochondrial protein import: specific recognition and membrane translocation of preproteins.

Authors:  M Kiebler; K Becker; N Pfanner; W Neupert
Journal:  J Membr Biol       Date:  1993-09       Impact factor: 1.843

5.  Protein import into mitochondria: the requirement for external ATP is precursor-specific whereas intramitochondrial ATP is universally needed for translocation into the matrix.

Authors:  C Wachter; G Schatz; B S Glick
Journal:  Mol Biol Cell       Date:  1994-04       Impact factor: 4.138

6.  Polypeptides traverse the mitochondrial envelope in an extended state.

Authors:  J Rassow; F U Hartl; B Guiard; N Pfanner; W Neupert
Journal:  FEBS Lett       Date:  1990-11-26       Impact factor: 4.124

7.  Yeast mitochondrial ATP-dependent protease: purification and comparison with the homologous rat enzyme and the bacterial ATP-dependent protease La.

Authors:  E Kutejová; G Durcová; E Surovková; S Kuzela
Journal:  FEBS Lett       Date:  1993-08-23       Impact factor: 4.124

8.  Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.

Authors:  K Liberek; J Marszalek; D Ang; C Georgopoulos; M Zylicz
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205

9.  Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli groES.

Authors:  S Rospert; T Junne; B S Glick; G Schatz
Journal:  FEBS Lett       Date:  1993-12-13       Impact factor: 4.124

10.  Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein.

Authors:  A J Caplan; M G Douglas
Journal:  J Cell Biol       Date:  1991-08       Impact factor: 10.539
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  10 in total

1.  Mitochondria are selective targets for the protective effects of heat shock against oxidative injury.

Authors:  B S Polla; S Kantengwa; D François; S Salvioli; C Franceschi; C Marsac; A Cossarizza
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

Review 2.  Hsp70--a multi-gene, multi-structure, multi-function family with potential clinical applications.

Authors:  U Feige; B S Polla
Journal:  Experientia       Date:  1994-11-30

Review 3.  Sepsis-induced cardiomyopathy: a review of pathophysiologic mechanisms.

Authors:  Anthony Flynn; Bhalaghuru Chokkalingam Mani; Paul J Mather
Journal:  Heart Fail Rev       Date:  2010-11       Impact factor: 4.214

4.  The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria.

Authors:  W Abdel-Razaq; D A Kendall; T E Bates
Journal:  Neurochem Res       Date:  2010-12-01       Impact factor: 3.996

Review 5.  The fates of proteins in cells.

Authors:  P Bohley
Journal:  Naturwissenschaften       Date:  1995-12

6.  Attenuation of sepsis-induced apoptosis by heat shock pretreatment in rats.

Authors:  H W Chen; C Hsu; S I Lue; R C Yang
Journal:  Cell Stress Chaperones       Date:  2000-07       Impact factor: 3.667

7.  Cytochrome c oxidase as the target of the heat shock protective effect in septic liver.

Authors:  Hsiang-Wen Chen; Hung-Tien Kuo; Tzong-Shi Lu; Shu-Jung Wang; Rei-Cheng Yang
Journal:  Int J Exp Pathol       Date:  2004-10       Impact factor: 1.925

Review 8.  Sepsis-induced cardiomyopathy.

Authors:  Francisco J Romero-Bermejo; Manuel Ruiz-Bailen; Julian Gil-Cebrian; Maria J Huertos-Ranchal
Journal:  Curr Cardiol Rev       Date:  2011-08

Review 9.  Roles of molecular chaperones in protein degradation.

Authors:  S A Hayes; J F Dice
Journal:  J Cell Biol       Date:  1996-02       Impact factor: 10.539

Review 10.  Cytosolic Quality Control of Mitochondrial Protein Precursors-The Early Stages of the Organelle Biogenesis.

Authors:  Anna M Lenkiewicz; Magda Krakowczyk; Piotr Bragoszewski
Journal:  Int J Mol Sci       Date:  2021-12-21       Impact factor: 5.923
  10 in total

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