| Literature DB >> 7983757 |
O Pleskoff1, M Seman, M Alizon.
Abstract
The antiviral effect of MS8209, an amphotericin B derivative, was studied in CD4+ cells transfected with a lacZ gene inducible upon human immunodeficiency virus type 1 (HIV-1) infection. MS8209 was shown to block virus entry after receptor binding and probably before virus-cell membrane fusion, but it had no effect on syncytium formation, although both processes are mediated by HIV-1 envelope proteins and CD4.Entities:
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Year: 1995 PMID: 7983757 PMCID: PMC188612 DOI: 10.1128/JVI.69.1.570-574.1995
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103