Literature DB >> 7980543

8-Amino-2'-deoxyadenosine: 2'-deoxythymidine base pairing: identification of novel reverse Hoogsteen mode in solution.

R K Kumar1, A D Gunjal, K N Ganesh.   

Abstract

A novel reversed Hoogsteen mode is observed for the base-pairing of 8-amino-2'-deoxyadenosine with 2'-deoxythymidine in low dielectric solvent. The results may have important significance for designing novel DNA duplexes and triplexes incorporating 8-amino-dA.

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Year:  1994        PMID： 7980543     DOI： 10.1006/bbrc.1994.2528

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  2 in total

1.  DNA-triplex stabilizing properties of 8-aminoguanine.

Authors:  R Soliva; R Güimil García; J R Blas; R Eritja; J L Asensio; C González; F J Luque; M Orozco
Journal:  Nucleic Acids Res       Date:  2000-11-15       Impact factor: 16.971

2.  Recognition of 5-aminouracil (U(#)) in the central strand of a DNA triplex: orientation selective binding of different third strand bases.

Authors:  V S Rana; K N Ganesh
Journal:  Nucleic Acids Res       Date:  2000-03-01       Impact factor: 16.971
  2 in total

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