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Literature DB >> 796728

Spontaneous mutation by mutagenic repair of spontaneous lesions in DNA.

P J Hastings, S K Quah, R C von Borstel.

Abstract

Strains of yeast carrying mutations in many of the steps in pathways repairing radiation-induced damage to DNA have enhanced spontaneous mutation rates. Most strains isolated because they have enhanced spontaneous mutation carry mutations in DNA repair systems. This suggests that much spontaneous mutation arises by mutagenic repair of spontaneous lesions.

Entities: Species

Mesh：

Year: 1976 PMID： 796728 DOI： 10.1038/264719a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

34 in total

1. Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae.

Authors: R H Schiestl; R D Gietz; P J Hastings; U Wintersberger
Journal: Mol Gen Genet Date: 1990-06

Review 2. Cell cycle control of DNA synthesis in budding yeast.

Authors: L H Johnston; N F Lowndes
Journal: Nucleic Acids Res Date: 1992-05-25 Impact factor: 16.971

3. A mutator nuclear gene inducing a wide spectrum of cytoplasmically inherited chlorophyll deficiences in barley.

Authors: A R Prina
Journal: Theor Appl Genet Date: 1992-11 Impact factor: 5.699

4. Cloning and integrative deletion of the RAD6 gene of Saccharomyces cerevisiae.

Authors: M Kupiec; G Simchen
Journal: Curr Genet Date: 1984-10 Impact factor: 3.886

5. Genetic control of enhanced mutability of mitochondrial DNA and gamma-ray sensitivity in Saccharomyces cerevisiae.

Authors: F Foury; A Goffeau
Journal: Proc Natl Acad Sci U S A Date: 1979-12 Impact factor: 11.205

6. The Utilization during Mitotic Cell Division of Loci Controlling Meiotic Recombination and Disjunction in DROSOPHILA MELANOGASTER.

Authors: B S Baker; A T Carpenter; P Ripoll
Journal: Genetics Date: 1978-11 Impact factor: 4.562

Spontaneous mutation by mutagenic repair of spontaneous lesions in DNA.

1. Interchromosomal and intrachromosomal recombination in rad 18 mutants of Saccharomyces cerevisiae.

Review 2. Cell cycle control of DNA synthesis in budding yeast.

3. A mutator nuclear gene inducing a wide spectrum of cytoplasmically inherited chlorophyll deficiences in barley.

4. Cloning and integrative deletion of the RAD6 gene of Saccharomyces cerevisiae.

5. Genetic control of enhanced mutability of mitochondrial DNA and gamma-ray sensitivity in Saccharomyces cerevisiae.

6. The Utilization during Mitotic Cell Division of Loci Controlling Meiotic Recombination and Disjunction in DROSOPHILA MELANOGASTER.

7. Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2.

8. Interaction of excision repair gene products and mitotic recombination functions in yeast.

9. Disruption of the RAD52 gene alters the spectrum of spontaneous SUP4-o mutations in Saccharomyces cerevisiae.

10. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair.