Literature DB >> 796682

Anomalies in the selection of mutants of Schizosaccharomyces pombe resistant to 8-azaguanine.

P McAthey.   

Abstract

Anomalies in selection render 8-azaguanine unsuitable as a selective agent for screening forward mutations in continuour cultures of Sch. pombe. This system may, however, provide tha basis for an enrichment method for the simultaneous isolation of mutants at two loci.

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Year:  1976        PMID： 796682     DOI： 10.1007/bf00332895

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  11 in total

1.  [Physiologic and genetic studies of adenine-dependant mutants of Schizosaccharomyces pombe; a contribution to the problem of pseudoallele].

Authors:  U LEUPOLD
Journal:  Schweiz Z Pathol Bakteriol       Date:  1957

2.  Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. I. Properties of the phosphoribosylpyrophosphate: glutamine amidotransferase of the wild strain and of a mutant desensitized towards feedback modifiers.

Authors:  M Nagy
Journal:  Biochim Biophys Acta       Date:  1970-03-18

3.  Mutants of Neurospora crassa resistant to 8-azaguanine.

Authors:  G R Hoffmann; H V Malling
Journal:  J Gen Microbiol       Date:  1974-08

4.  Altered enzymes in drug-resistant variants of mammalian tissue culture cells.

Authors:  J D Sharp; N E Capecchi; M R Capecchi
Journal:  Proc Natl Acad Sci U S A       Date:  1973-11       Impact factor: 11.205

5.  The spontaneous azaguanine-resistant mutants of diploid human fibroblasts.

Authors:  R DeMars; K R Held
Journal:  Humangenetik       Date:  1972

6.  Mammalian cell genetics. I. Selection and characterization of mutations auxotrophic for L-glutamine or resistant to 8-azaguanine in Chinese hamster cells in vitro.

Authors:  E H Chu; P Brimer; K B Jacobson; E V Merriam
Journal:  Genetics       Date:  1969-06       Impact factor: 4.562

7.  Mutagenesis of cultured mammalian cells by X-radiation and ultraviolet light.

Authors:  B A Bridges; J Huckle
Journal:  Mutat Res       Date:  1970-08       Impact factor: 2.433

8.  Genetic analysis of azaguanine resistance in an established mouse cell line.

Authors:  J Morrow
Journal:  Genetics       Date:  1970-06       Impact factor: 4.562

9.  Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

Authors:  E H Chu; H V Malling
Journal:  Proc Natl Acad Sci U S A       Date:  1968-12       Impact factor: 11.205

10.  The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT).

Authors:  A A van Zeeland; C E de Ruijter; J W Simons
Journal:  Mutat Res       Date:  1974-07       Impact factor: 2.433
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