| Literature DB >> 7966230 |
S R Bartz1, C D Pauza, J Ivanyi, S Jindal, W J Welch, M Malkovsky.
Abstract
The possible physical association of heat shock proteins (Hsp's) with immunodeficiency viruses (HIV and SIV) has been examined. The virions were purified by a) polyethylene glycol (PEG) precipitation and Sepharose 4B filtration, b) PEG precipitation and centrifugation over a Renografin gradient, or c) PEG precipitation and Matrex Cellufine Sulfate affinity chromatography. Western blotting revealed an Hsp60 related protein associated with HIV and SIV. Other Hsp's (such as Hsp70) were not detected, suggesting a specific interaction between Hsp60 and viral factors.Entities:
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Year: 1994 PMID： 7966230 DOI： 10.1111/j.1600-0684.1994.tb00116.x
Source DB: PubMed Journal: J Med Primatol ISSN： 0047-2565 Impact factor: 0.667