Literature DB >> 7966144

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

R E Dolle1, J Singh, J Rinker, D Hoyer, C V Prasad, T L Graybill, J M Salvino, C T Helaszek, R E Miller, M A Ator.   

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Year:  1994        PMID： 7966144     DOI： 10.1021/jm00049a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  4 in total

1.  T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection.

Authors:  L K Clayton; Y Ghendler; E Mizoguchi; R J Patch; T D Ocain; K Orth; A K Bhan; V M Dixit; E L Reinherz
Journal:  EMBO J       Date:  1997-05-01       Impact factor: 11.598

Review 2.  Small Molecule Active Site Directed Tools for Studying Human Caspases.

Authors:  Marcin Poreba; Aleksandra Szalek; Paulina Kasperkiewicz; Wioletta Rut; Guy S Salvesen; Marcin Drag
Journal:  Chem Rev       Date:  2015-11-09       Impact factor: 60.622

Review 3.  Caspase substrates and inhibitors.

Authors:  Marcin Poreba; Aleksandra Strózyk; Guy S Salvesen; Marcin Drag
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-08-01       Impact factor: 10.005

4.  Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells.

Authors:  S T Park; G P Nolan; X H Sun
Journal:  J Exp Med       Date:  1999-02-01       Impact factor: 14.307
  4 in total

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