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Literature DB >> 7961670

Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins.

W J Feaver¹, N L Henry, D A Bushnell, M H Sayre, J H Brickner, O Gileadi, R D Kornberg.

Abstract

Genes encoding both the 66- and the 43-kDa subunits of yeast RNA polymerase II initiation factor a, designated TFA1 and TFA2, have been isolated. Both genes are essential for cell viability. The bacterially expressed gene products could replace factor a in transcription in vitro, and both recombinant subunits were required for activity. The deduced amino acid sequences of the TFA1 and TFA2 gene products were homologous to those of the large and small subunits of human TFIIE, respectively, identifying factor a as the yeast homolog of TFIIE.

Entities: Gene Species

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Year: 1994 PMID： 7961670

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

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Cited

19 in total

1. Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters.

Authors: R Belotserkovskaya; D E Sterner; M Deng; M H Sayre; P M Lieberman; S L Berger
Journal: Mol Cell Biol Date: 2000-01 Impact factor: 4.272

2. Genetic analysis of the large subunit of yeast transcription factor IIE reveals two regions with distinct functions.

Authors: N H Kuldell; S Buratowski
Journal: Mol Cell Biol Date: 1997-09 Impact factor: 4.272

3. Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo.

Authors: Z W Sun; M Hampsey
Journal: Mol Cell Biol Date: 1996-04 Impact factor: 4.272

Review 4. Molecular genetics of the RNA polymerase II general transcriptional machinery.

Authors: M Hampsey
Journal: Microbiol Mol Biol Rev Date: 1998-06 Impact factor: 11.056

5. Purification of the Drosophila RNA polymerase II general transcription factors.

Authors: R J Austin; M D Biggin
Journal: Proc Natl Acad Sci U S A Date: 1996-06-11 Impact factor: 11.205

6. Yeast RNA polymerase II transcription in vitro is inhibited in the presence of nucleotide excision repair: complementation of inhibition by Holo-TFIIH and requirement for RAD26.

Authors: Z You; W J Feaver; E C Friedberg
Journal: Mol Cell Biol Date: 1998-05 Impact factor: 4.272

Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins.

1. Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters.

2. Genetic analysis of the large subunit of yeast transcription factor IIE reveals two regions with distinct functions.

3. Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo.

Review 4. Molecular genetics of the RNA polymerase II general transcriptional machinery.

5. Purification of the Drosophila RNA polymerase II general transcription factors.

6. Yeast RNA polymerase II transcription in vitro is inhibited in the presence of nucleotide excision repair: complementation of inhibition by Holo-TFIIH and requirement for RAD26.

7. Functional interchangeability of TFIIIB components from yeast and human cells in vitro.

8. Activation of RNA polymerase II by topologically linked DNA-tracking proteins.

9. The Cys4 zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition.

10. Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface.