Literature DB >> 7960129

Characterization of an antigenic oligosaccharide from Leptospira interrogans serovar pomona and its role in immunity.

A Midwinter1, T Vinh, S Faine, B Adler.   

Abstract

An antigenic oligosaccharide fraction derived from the lipopolysaccharide of Leptospira interrogans serovar pomona was isolated by endo-glycosidase H digestion and column chromatography. The oligosaccharide contained rhamnose, ribose, glucose, and glucosamine and inhibited the binding of opsonic, protective monoclonal antibodies directed against the lipopolysaccharide. When conjugated to diphtheria toxoid, the oligosaccharide elicited the production of agglutinating, opsonic antibodies.

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Year:  1994        PMID： 7960129      PMCID： PMC303291          DOI： 10.1128/iai.62.12.5477-5482.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  29 in total

1.  Dairy farm fever in New Zealand: isolation of L pomona and L hardjo from a local outbreak.

Authors:  B W Christmas; J M Bragger; D G Till
Journal:  N Z Med J       Date:  1974-05-08

2.  Isolation of the antigen-active components from leptospiral serovar-specific lipopolysaccharide antigen by mild acid hydrolysis.

Authors:  Y Kawaoka; M Naiki; R Yanagawa
Journal:  Nihon Juigaku Zasshi       Date:  1982-06

3.  Risks of contracting leptospirosis on the dairy farm.

Authors:  D K Blackmore; L M Schollum
Journal:  N Z Med J       Date:  1982-09-22

4.  A dot-immunobinding assay for monoclonal and other antibodies.

Authors:  R Hawkes; E Niday; J Gordon
Journal:  Anal Biochem       Date:  1982-01-01       Impact factor: 3.365

5.  Isolation of antigenically active components from leptospiral serovar-specific lipopolysaccharide antigen by alkaline treatment.

Authors:  M Tsuji; Y Kawaoka; M Naiki; R Yanagawa
Journal:  Microbiol Immunol       Date:  1981       Impact factor: 1.955

6.  The antibodies involved in the human immune response to leptospiral infection.

Authors:  B Adler; S Faine
Journal:  J Med Microbiol       Date:  1978-11       Impact factor: 2.472

7.  Serological and protective-antibody responses of rabbits to leptospiral antigens.

Authors:  B Adler; S Faine
Journal:  J Med Microbiol       Date:  1978-11       Impact factor: 2.472

8.  Susceptibility of mice treated with cyclophosphamide to lethal infection with Leptospira interrogans Serovar pomona.

Authors:  B Adler; S Faine
Journal:  Infect Immun       Date:  1976-09       Impact factor: 3.441

9.  Meningococcal lipopolysaccharide (LPS)-derived oligosaccharide-protein conjugates evoke outer membrane protein- but not LPS-specific bactericidal antibodies in mice: influence of adjuvants.

Authors:  A F Verheul; J A Van Gaans; E J Wiertz; H Snippe; J Verhoef; J T Poolman
Journal:  Infect Immun       Date:  1993-01       Impact factor: 3.441

10.  Detection of specific anti-leptospiral immunoglobulins M and G in human serum by solid-phase enzyme-linked immunosorbent assay.

Authors:  B Adler; A M Murphy; S A Locarnini; S Faine
Journal:  J Clin Microbiol       Date:  1980-05       Impact factor: 5.948
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  6 in total

Review 1.  Leptospirosis.

Authors:  P N Levett
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

Review 2.  The leptospiral outer membrane.

Authors:  David A Haake; Wolfram R Zückert
Journal:  Curr Top Microbiol Immunol       Date:  2015       Impact factor: 4.291

3.  Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar Copenhageni.

Authors:  M Mitchison; D M Bulach; T Vinh; K Rajakumar; S Faine; B Adler
Journal:  J Bacteriol       Date:  1997-02       Impact factor: 3.490

4.  Leptospirosis after recreational exposure to water in the Yaeyama islands, Japan.

Authors:  Masashi Narita; Shigeki Fujitani; David A Haake; David L Paterson
Journal:  Am J Trop Med Hyg       Date:  2005-10       Impact factor: 2.345

5.  A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2.

Authors:  Nanette L S Que-Gewirth; Anthony A Ribeiro; Suzanne R Kalb; Robert J Cotter; Dieter M Bulach; Ben Adler; Isabelle Saint Girons; Catherine Werts; Christian R H Raetz
Journal:  J Biol Chem       Date:  2004-03-24       Impact factor: 5.157

6.  Leptospirosis vaccines.

Authors:  Zhijun Wang; Li Jin; Alicja Wegrzyn
Journal:  Microb Cell Fact       Date:  2007-12-11       Impact factor: 5.328
  6 in total

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