Literature DB >> 7954890

An analysis of the sequence of part of the right arm of chromosome II of S. cerevisiae reveals new genes encoding an amino-acid permease and a carboxypeptidase.

F Nasr1, A M Bécam, E Grzybowska, M Zagulski, P P Slonimski, C J Herbert.   

Abstract

We have analysed two new genes, YBR1007 and YBR1015, discovered during the systematic sequencing of chromosome II of S. cerevisiae. YBR1007 shows strong similarities to amino-acid permeases, in particular the high-affinity proline permeases of S. cerevisiae and A. nidulans. The number and position of the predicted membrane-spanning domains suggest a conserved structure for these proteins, with 12 trans-membrane domains. YBR1015 shows strong similarities to serine carboxypeptidases; all three residues of the "catalytic triad" typical of this family of enzymes are conserved in the YBR1015 protein. In a preliminary functional analysis we have created a null allele of the YBR1015 gene, and shown that it is not essential for cellular viability.

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Year:  1994        PMID： 7954890     DOI： 10.1007/BF00326297

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  29 in total

1.  Evolutionary divergence plots of homologous proteins.

Authors:  S Brouillet; J L Risler; A Hénaut; P P Slonimski
Journal:  Biochimie       Date:  1992-06       Impact factor: 4.079

2.  One-step transformation of yeast in stationary phase.

Authors:  D C Chen; B C Yang; T T Kuo
Journal:  Curr Genet       Date:  1992-01       Impact factor: 3.886

3.  GAP1, the general amino acid permease gene of Saccharomyces cerevisiae. Nucleotide sequence, protein similarity with the other bakers yeast amino acid permeases, and nitrogen catabolite repression.

Authors:  J C Jauniaux; M Grenson
Journal:  Eur J Biochem       Date:  1990-05-31

4.  Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide.

Authors:  L A Valls; C P Hunter; J H Rothman; T H Stevens
Journal:  Cell       Date:  1987-03-13       Impact factor: 41.582

Review 5.  How many yeast genes code for membrane-spanning proteins?

Authors:  A Goffeau; P Slonimski; K Nakai; J L Risler
Journal:  Yeast       Date:  1993-07       Impact factor: 3.239

6.  Long range control circuits within mitochondria and between nucleus and mitochondria. I. Methodology and phenomenology of suppressors.

Authors:  G Dujardin; P Pajot; O Groudinsky; P P Slonimski
Journal:  Mol Gen Genet       Date:  1980

7.  Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity.

Authors:  J R Winther; P Sørensen
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

8.  Cloning and sequencing of the Saccharomyces cerevisiae gene LYP1 coding for a lysine-specific permease.

Authors:  H Sychrova; M R Chevallier
Journal:  Yeast       Date:  1993-07       Impact factor: 3.239

9.  Structure of wheat serine carboxypeptidase II at 3.5-A resolution. A new class of serine proteinase.

Authors:  D I Liao; S J Remington
Journal:  J Biol Chem       Date:  1990-04-25       Impact factor: 5.157

10.  The lysP gene encodes the lysine-specific permease.

Authors:  C Steffes; J Ellis; J Wu; B P Rosen
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490
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  4 in total

Review 1.  Vacuolar hydrolysis and efflux: current knowledge and unanswered questions.

Authors:  Katherine R Parzych; Daniel J Klionsky
Journal:  Autophagy       Date:  2018-11-22       Impact factor: 16.016

2.  The Kluyveromyces lactis CPY homologous genes: cloning and characterization of the KlPCL1 gene.

Authors:  D Staneva; D Uccelletti; P Venkov; G Miloshev; C Palleschi
Journal:  Folia Microbiol (Praha)       Date:  2008-08-31       Impact factor: 2.099

3.  A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae.

Authors:  Katherine R Parzych; Aileen Ariosa; Muriel Mari; Daniel J Klionsky
Journal:  Mol Biol Cell       Date:  2018-03-22       Impact factor: 4.138

4.  Complete DNA sequence of yeast chromosome II.

Authors:  H Feldmann; M Aigle; G Aljinovic; B André; M C Baclet; C Barthe; A Baur; A M Bécam; N Biteau; E Boles; T Brandt; M Brendel; M Brückner; F Bussereau; C Christiansen; R Contreras; M Crouzet; C Cziepluch; N Démolis; T Delaveau; F Doignon; H Domdey; S Düsterhus; E Dubois; B Dujon; M El Bakkoury; K D Entian; M Feurmann; W Fiers; G M Fobo; C Fritz; H Gassenhuber; N Glandsdorff; A Goffeau; L A Grivell; M de Haan; C Hein; C J Herbert; C P Hollenberg; K Holmstrøm; C Jacq; M Jacquet; J C Jauniaux; J L Jonniaux; T Kallesøe; P Kiesau; L Kirchrath; P Kötter; S Korol; S Liebl; M Logghe; A J Lohan; E J Louis; Z Y Li; M J Maat; L Mallet; G Mannhaupt; F Messenguy; T Miosga; F Molemans; S Müller; F Nasr; B Obermaier; J Perea; A Piérard; E Piravandi; F M Pohl; T M Pohl; S Potier; M Proft; B Purnelle; M Ramezani Rad; M Rieger; M Rose; I Schaaff-Gerstenschläger; B Scherens; C Schwarzlose; J Skala; P P Slonimski; P H Smits; J L Souciet; H Y Steensma; R Stucka; A Urrestarazu; Q J van der Aart; L van Dyck; A Vassarotti; I Vetter; F Vierendeels; S Vissers; G Wagner; P de Wergifosse; K H Wolfe; M Zagulski; F K Zimmermann; H W Mewes; K Kleine
Journal:  EMBO J       Date:  1994-12-15       Impact factor: 11.598
  4 in total

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