Literature DB >> 7950351

Odor discrimination deficits in schizophrenia: association with eye movement dysfunction.

D Malaspina1, A D Wray, J H Friedman, X Amador, S Yale, A Hasan, J M Gorman, C A Kaufmann.   

Abstract

Odor discrimination deficits were found in 80% of 20 schizophrenia patients and in none of the 20 age- and sex-matched comparison subjects. Olfactory discrimination was reliably measured in the patients. Twelve patients in this study also had smooth pursuit eye movement (SPEM) qualitatively recorded. The olfactory discrimination scores were highly correlated to SPEM but not to other clinical measures. This correlation suggests a shared neurobiology, possibly involving working memory.

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Year:  1994        PMID： 7950351     DOI： 10.1176/jnp.6.3.273

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  10 in total

Review 1.  Scent of a disorder: olfactory functioning in schizophrenia.

Authors:  Paul J Moberg; Bruce I Turetsky
Journal:  Curr Psychiatry Rep       Date:  2003-08       Impact factor: 5.285

2.  Olfactory identification and Stroop interference converge in schizophrenia.

Authors:  S E Purdon
Journal:  J Psychiatry Neurosci       Date:  1998-05       Impact factor: 6.186

3.  Odor identification, eye tracking and deficit syndrome schizophrenia.

Authors:  Dolores Malaspina; Eliza Coleman; Raymond R Goetz; Jill Harkavy-Friedman; Cheryl Corcoran; Xavier Amador; Scott Yale; Jack M Gorman
Journal:  Biol Psychiatry       Date:  2002-05-15       Impact factor: 13.382

4.  Paternal age related schizophrenia (PARS): Latent subgroups detected by k-means clustering analysis.

Authors:  Hyejoo Lee; Dolores Malaspina; Hongshik Ahn; Mary Perrin; Mark G Opler; Karine Kleinhaus; Susan Harlap; Raymond Goetz; Daniel Antonius
Journal:  Schizophr Res       Date:  2011-02-26       Impact factor: 4.939

5.  Olfactory deficits, cognition and negative symptoms in early onset psychosis.

Authors:  Cheryl Corcoran; Agnes Whitaker; Eliza Coleman; Jane Fried; Judith Feldman; Nora Goudsmit; Dolores Malaspina
Journal:  Schizophr Res       Date:  2005-08-26       Impact factor: 4.939

6.  Olfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression.

Authors:  Jennifer L Hellier; Nicole L Arevalo; Megan J Blatner; An K Dang; Amy C Clevenger; Catherine E Adams; Diego Restrepo
Journal:  Brain Res       Date:  2010-08-13       Impact factor: 3.252

7.  Olfactory acuity is associated with mood and function in a pilot study of stable bipolar disorder patients.

Authors:  Caitlin Hardy; Mary Rosedale; Julie W Messinger; Karine Kleinhaus; Nicole Aujero; Hanna Silva; Raymond R Goetz; Deborah Goetz; Jill Harkavy-Friedman; Dolores Malaspina
Journal:  Bipolar Disord       Date:  2012-02       Impact factor: 6.744

8.  Perceptual pathways to hallucinogenesis.

Authors:  Andrew D Sheldon; Eren Kafadar; Victoria Fisher; Maximillian S Greenwald; Fraser Aitken; Alyson M Negreira; Scott W Woods; Albert R Powers
Journal:  Schizophr Res       Date:  2022-02-23       Impact factor: 4.662

9.  The influence of semantic processing on odor identification ability in schizophrenia.

Authors:  Vidyulata Kamath; Bruce I Turetsky; Sarah C Seligman; Dana M Marchetto; Jeffrey B Walker; Paul J Moberg
Journal:  Arch Clin Neuropsychol       Date:  2013-03-28       Impact factor: 2.813

Review 10.  Scents and nonsense: olfactory dysfunction in schizophrenia.

Authors:  Bruce I Turetsky; Chang-Gyu Hahn; Karin Borgmann-Winter; Paul J Moberg
Journal:  Schizophr Bull       Date:  2009-09-30       Impact factor: 9.306
  10 in total

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