| Literature DB >> 7949222 |
M Vanelli1, A De Fanti, S Cantoni, G Chiari.
Abstract
The follow-up study of a patient with permanent diabetes (DM) unrelated to islet cell antibody and anti-insulin antibodies and occurring 10 years after a transient neonatal DM episode is reported. A latent defect in insulin release was proved. It produced transient glucosuria during intercurrent illnesses and permanent hyperglycaemia and a decrease in growth velocity [with high stimulated growth hormone and low insulin-like growth factor I (IGF-I)] at the onset of puberty. After insulin therapy was re-introduced, catch-up growth and normalization of the blood glucose and IGF-I levels were noted.Entities:
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Year: 1994 PMID： 7949222 DOI： 10.1007/bf00570547
Source DB: PubMed Journal: Acta Diabetol ISSN： 0940-5429 Impact factor: 4.280