Literature DB >> 7946911

Inhibition of lipid peroxidation by a new family of iron chelators. Comparison with desferrioxamine.

S Rachidi1, C Coudray, P Baret, G Gelon, J L Pierre, A Favier.   

Abstract

Catechol derived siderophores are the most powerful currently known iron chelators. We have intended tripodal ligands built with o,o' dihydroxy biaryl subunits (A, B, and C). We described antioxidant properties of this new family of iron chelators. Superoxide-dependent hydroxyl radical system was used. Peroxidation of different lipid-containing systems (liposomes, erythrocyte membrane ghosts, tissue homogenates) were also investigated. The antioxidant properties of these new chelators have been related to that of desferrioxamine as a reference compound. In general manner, the results depended mainly on the model used in the assay. However, C presents an antioxidant effect close to that of desferrioxamine.

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Year:  1994        PMID： 7946911     DOI： 10.1007/bf02917219

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  20 in total

Review 1.  The role of iron in the initiation of lipid peroxidation.

Authors:  G Minotti; S D Aust
Journal:  Chem Phys Lipids       Date:  1987 Jul-Sep       Impact factor: 3.329

2.  Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates: is it a mechanism for hydroxyl radical production in biochemical systems?

Authors:  B Halliwell
Journal:  FEBS Lett       Date:  1978-08-15       Impact factor: 4.124

3.  Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy.

Authors:  M Grootveld; J D Bell; B Halliwell; O I Aruoma; A Bomford; P J Sadler
Journal:  J Biol Chem       Date:  1989-03-15       Impact factor: 5.157

4.  Further studies on ethylene formation from alpha-keto-gamma-methylthiobutyric acid or beta-methylthiopropionaldehyde by peroxidase in the presence of sulfite and oxygen.

Authors:  S F Yang
Journal:  J Biol Chem       Date:  1969-08-25       Impact factor: 5.157

5.  Studies in acute iron poisoning. I. Desferrioxamine in the treatment of acute iron poisoning: clinical observations, experimental studies, and theoretical considerations.

Authors:  C F Whitten; G W Gibson; M H Good; J F Goodwin; A J Brough
Journal:  Pediatrics       Date:  1965-09       Impact factor: 7.124

6.  Formation of thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts: the role of superoxide and hydroxyl radicals.

Authors:  B Halliwell; J M Gutteridge
Journal:  FEBS Lett       Date:  1981-06-15       Impact factor: 4.124

7.  Lipid peroxidation of erythrocyte membrane induced by xanthine oxidase system: modification of superoxide dismutase effect by hemoglobin.

Authors:  T Miura; T Ogiso
Journal:  Chem Pharm Bull (Tokyo)       Date:  1982-10       Impact factor: 1.645

8.  Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine.

Authors:  J M Gutteridge; R Richmond; B Halliwell
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

9.  Malondialdehyde formation from lipid peroxides in the thiobarbituric acid test: the role of lipid radicals, iron salts, and metal chelators.

Authors:  J M Gutteridge; G J Quinlan
Journal:  J Appl Biochem       Date:  1983 Aug-Oct

10.  The role of superoxide and hydroxyl radicals in phospholipid peroxidation catalysed by iron salts.

Authors:  J M Gutteridge
Journal:  FEBS Lett       Date:  1982-12-27       Impact factor: 4.124
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  2 in total

1.  Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells.

Authors:  Yutaka Niihara; Junli Ge; Oded Shalev; Huiyuan Wu; Amy Tu; Kouichi R Tanaka
Journal:  BMC Clin Pharmacol       Date:  2002-10-24

2.  The Availability of Iron Is Involved in the Murine Experimental Toxoplasma gondii Infection Outcome.

Authors:  Mário Cézar Oliveira; Loyane Bertagnolli Coutinho; Marcos Paulo Oliveira Almeida; Marisol Pallete Briceño; Ester Cristina Borges Araujo; Neide Maria Silva
Journal:  Microorganisms       Date:  2020-04-14
  2 in total

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