Literature DB >> 7945151

Variability and stability in cognitive abilities are largely genetic later in life.

R Plomin1, N L Pedersen, P Lichtenstein, G E McClearn.   

Abstract

The powerful quantitative genetic design of identical and fraternal twins reared apart (112 pairs) and matched twins reared together (111 pairs) was employed to assess the extent of genetic influence on individual differences in cognitive abilities during the last half of the life span. General cognitive ability yielded a heritability estimate of about .80 in two assessments 3 years apart as part of the Swedish Adoption/Twin Study of Aging. This is one of the highest heritabilities reported for a behavioral trait. Across the two ages, average heritabilities are about .60 for verbal tests, .50 for spatial and speed-of-processing tests, and .40 for memory tests. For general cognitive ability, the phenotypic stability across the 3 years is .92 and stable genetic factors account for nearly 90% this stability. These findings suggest that general cognitive ability is a reasonable target for research that aims to identify specific genes for complex traits.

Mesh:

Year:  1994        PMID: 7945151     DOI: 10.1007/bf01067188

Source DB:  PubMed          Journal:  Behav Genet        ISSN: 0001-8244            Impact factor:   2.805


  11 in total

1.  Comparative adaptational, social, and psychometric data on the life histories of senescent twin pairs.

Authors:  F J KALLMANN; L FEINGOLD; E BONDY
Journal:  Am J Hum Genet       Date:  1951-03       Impact factor: 11.025

2.  The promise and pitfalls of molecular genetics.

Authors:  P Aldhous
Journal:  Science       Date:  1992-07-10       Impact factor: 47.728

3.  The Swedish Adoption Twin Study of Aging: an update.

Authors:  N L Pedersen; G E McClearn; R Plomin; J R Nesselroade; S Berg; U DeFaire
Journal:  Acta Genet Med Gemellol (Roma)       Date:  1991

Review 4.  The role of inheritance in behavior.

Authors:  R Plomin
Journal:  Science       Date:  1990-04-13       Impact factor: 47.728

5.  Growing up and growing apart: a developmental meta-analysis of twin studies.

Authors:  K McCartney; M J Harris; F Bernieri
Journal:  Psychol Bull       Date:  1990-03       Impact factor: 17.737

Review 6.  Partitioning environmental and genetic contributions to behavioral development.

Authors:  J C Loehlin
Journal:  Am Psychol       Date:  1989-10

7.  Modeling IQ change: evidence from the Texas Adoption Project.

Authors:  J C Loehlin; J M Horn; L Willerman
Journal:  Child Dev       Date:  1989-08

Review 8.  Genetics of specific cognitive abilities.

Authors:  J C DeFries; S G Vandenberg; G E McClearn
Journal:  Annu Rev Genet       Date:  1976       Impact factor: 16.830

9.  The Louisville Twin Study: developmental synchronies in behavior.

Authors:  R S Wilson
Journal:  Child Dev       Date:  1983-04

10.  Genetic influence on general mental ability increases between infancy and middle childhood.

Authors:  D W Fulker; J C DeFries; R Plomin
Journal:  Nature       Date:  1988 Dec 22-29       Impact factor: 49.962

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  24 in total

1.  Similar prefrontal cortical activities between general fluid intelligence and visuospatial working memory tasks in preschool children as revealed by optical topography.

Authors:  Mariko Kuwajima; Toshiyuki Sawaguchi
Journal:  Exp Brain Res       Date:  2010-09-19       Impact factor: 1.972

Review 2.  Genetic expression outside the skin: clues to mechanisms of Genotype x Environment interaction.

Authors:  David Reiss; Leslie D Leve
Journal:  Dev Psychopathol       Date:  2007

3.  Mapping genetic influences on ventricular structure in twins.

Authors:  Yi-Yu Chou; Natasha Leporé; Ming-Chang Chiang; Christina Avedissian; Marina Barysheva; Katie L McMahon; Greig I de Zubicaray; Matthew Meredith; Margaret J Wright; Arthur W Toga; Paul M Thompson
Journal:  Neuroimage       Date:  2008-11-07       Impact factor: 6.556

4.  Heritability of cognitive traits among siblings with a parental history of Alzheimer's disease.

Authors:  Burcu F Darst; Rebecca L Koscik; Bruce P Hermann; Asenath La Rue; Mark A Sager; Sterling C Johnson; Corinne D Engelman
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

5.  Storage and executive components of working memory: integrating cognitive psychology and behavior genetics in the study of aging.

Authors:  William S Kremen; Hong Xian; Kristen C Jacobson; Lindon J Eaves; Carol E Franz; Matthew S Panizzon; Seth A Eisen; Andrew Crider; Michael J Lyons
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2008-03       Impact factor: 4.077

6.  Placebo effects in cognitive training.

Authors:  Cyrus K Foroughi; Samuel S Monfort; Martin Paczynski; Patrick E McKnight; P M Greenwood
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-20       Impact factor: 11.205

7.  Continuity of genetic and environmental influences on cognition across the life span: a meta-analysis of longitudinal twin and adoption studies.

Authors:  Elliot M Tucker-Drob; Daniel A Briley
Journal:  Psychol Bull       Date:  2014-03-10       Impact factor: 17.737

8.  Kraepelin was right: a latent class analysis of symptom dimensions in patients and controls.

Authors:  Eske M Derks; Judith Allardyce; Marco P Boks; Jeroen K Vermunt; Ron Hijman; Roel A Ophoff
Journal:  Schizophr Bull       Date:  2010-09-23       Impact factor: 9.306

9.  A biometric latent curve analysis of memory decline in older men of the NAS-NRC twin registry.

Authors:  John J McArdle; Brenda L Plassman
Journal:  Behav Genet       Date:  2009-04-29       Impact factor: 2.805

10.  A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

Authors:  Anna C Need; Deborah K Attix; Jill M McEvoy; Elizabeth T Cirulli; Kristen L Linney; Priscilla Hunt; Dongliang Ge; Erin L Heinzen; Jessica M Maia; Kevin V Shianna; Michael E Weale; Lynn F Cherkas; Gail Clement; Tim D Spector; Greg Gibson; David B Goldstein
Journal:  Hum Mol Genet       Date:  2009-09-04       Impact factor: 6.150

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