OBJECTIVE: The authors evaluated the potential use of nonheartbeating (NHB) cadaver donors as an additional source to the current supply of brain-dead cadaver donors. SUMMARY BACKGROUND DATA: The numbers of cadaveric donors has not increased significantly during the last 5 years, despite a rising need for transplantable organs. Any improvement in cadaveric organ procurement will depend on the use of previously unrecognized potential donors. METHODS: During a 2-year period, 24 kidneys were retrieved from 12 NHB donors. Nineteen kidneys were transplanted. RESULTS: These kidneys sustained a mean warm ischemia time of 26 minutes (range 20-35 min). A mean lowest creatinine level of 2.0 mg/dL, (range 1.1-3.0 mg/dL), the rate of postoperative dialysis (22%), and a 1-year graft survival rate of 76% for kidneys from NHB-donated kidneys compare favorably to expected results achieved nationally from brain-dead cadaveric donors. CONCLUSIONS: Nonheartbeating donor kidneys can yield acceptable graft function and be of no disadvantage to recipients of cadaver transplants.
OBJECTIVE: The authors evaluated the potential use of nonheartbeating (NHB) cadaver donors as an additional source to the current supply of brain-dead cadaver donors. SUMMARY BACKGROUND DATA: The numbers of cadaveric donors has not increased significantly during the last 5 years, despite a rising need for transplantable organs. Any improvement in cadaveric organ procurement will depend on the use of previously unrecognized potential donors. METHODS: During a 2-year period, 24 kidneys were retrieved from 12 NHB donors. Nineteen kidneys were transplanted. RESULTS: These kidneys sustained a mean warm ischemia time of 26 minutes (range 20-35 min). A mean lowest creatinine level of 2.0 mg/dL, (range 1.1-3.0 mg/dL), the rate of postoperative dialysis (22%), and a 1-year graft survival rate of 76% for kidneys from NHB-donated kidneys compare favorably to expected results achieved nationally from brain-dead cadaveric donors. CONCLUSIONS: Nonheartbeating donor kidneys can yield acceptable graft function and be of no disadvantage to recipients of cadaver transplants.
Authors: F O Belzer; R M Hoffman; R J Stratta; A D'Alessandro; J Pirsch; M Kalayoglu; H W Sollinger Journal: Transplant Proc Date: 1989-02 Impact factor: 1.066
Authors: A M Castelao; J M Griñó; C González; E Franco; S GilVernet; E Andrés; D Serón; J Torras; F Moreso; J Alsina Journal: Transplant Proc Date: 1993-02 Impact factor: 1.066
Authors: N Matsuno; M Kozaki; E Sakurai; M Uchiyama; T Iwahori; K Kozaki; K Kono; M Tanaka; T Tamaki; I Tamaki Journal: Transplant Proc Date: 1993-02 Impact factor: 1.066
Authors: Sam D Shemie; Andrew J Baker; Greg Knoll; William Wall; Graeme Rocker; Daniel Howes; Janet Davidson; Joe Pagliarello; Jane Chambers-Evans; Sandra Cockfield; Catherine Farrell; Walter Glannon; William Gourlay; David Grant; Stéphan Langevin; Brian Wheelock; Kimberly Young; John Dossetor Journal: CMAJ Date: 2006-10-10 Impact factor: 8.262
Authors: Peter L Abt; Niraj M Desai; Michael D Crawford; Lisa M Forman; Joseph W Markmann; Kim M Olthoff; James F Markmann Journal: Ann Surg Date: 2004-01 Impact factor: 12.969