Literature DB >> 17124739

National recommendations for donation after cardiocirculatory death in Canada: Donation after cardiocirculatory death in Canada.

Sam D Shemie1, Andrew J Baker, Greg Knoll, William Wall, Graeme Rocker, Daniel Howes, Janet Davidson, Joe Pagliarello, Jane Chambers-Evans, Sandra Cockfield, Catherine Farrell, Walter Glannon, William Gourlay, David Grant, Stéphan Langevin, Brian Wheelock, Kimberly Young, John Dossetor.   

Abstract

These recommendations are the result of a national, multidisciplinary, year-long process to discuss whether and how to proceed with organ donation after cardiocirculatory death (DCD) in Canada. A national forum was held in February 2005 to discuss and develop recommendations on the principles, procedures and practice related to DCD, including ethical and legal considerations. At the forum's conclusion, a strong majority of participants supported proceeding with DCD programs in Canada. The forum also recognized the need to formulate and emphasize core values to guide the development of programs and protocols based on the medical, ethical and legal framework established at this meeting. Although end-of-life care should routinely include the opportunity to donate organs and tissues, the duty of care toward dying patients and their families remains the dominant priority of health care teams. The complexity and profound implications of death are recognized and should be respected, along with differing personal, ethnocultural and religious perspectives on death and donation. Decisions around withdrawal of life-sustaining therapies, management of the dying process and the determination of death by cardiocirculatory criteria should be separate from and independent of donation and transplant processes. The recommendations in this report are intended to guide individual programs, regional health authorities and jurisdictions in the development of DCD protocols. Programs will develop based on local leadership and advance planning that includes education and engagement of stakeholders, mechanisms to assure safety and quality and public information. We recommend that programs begin with controlled DCD within the intensive care unit where (after a consensual decision to withdraw life-sustaining therapy) death is anticipated, but has not yet occurred, and unhurried consent discussions can be held. Uncontrolled donation (where death has occurred after unanticipated cardiac arrest) should only be considered after a controlled DCD program is well established. Although we recommend that programs commence with kidney donation, regional transplant expertise may guide the inclusion of other organs. The impact of DCD, including pre-and post-mortem interventions, on donor family experiences, organ availability, graft function and recipient survival should be carefully documented and studied.

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Year:  2006        PMID: 17124739      PMCID: PMC1635157          DOI: 10.1503/cmaj.060895

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  49 in total

1.  The sequence of withdrawing life-sustaining treatment from patients.

Authors:  D A Asch; K Faber-Langendoen; J A Shea; N A Christakis
Journal:  Am J Med       Date:  1999-08       Impact factor: 4.965

2.  Importance of machine perfusion flow in kidney preservation.

Authors:  N Matsuno; K Kozaki; H Degawa; Y Narumi; N Suzuki; K Kikuchi; M Uchiyama; E Sakurai; M Kozaki; T Nagao
Journal:  Transplant Proc       Date:  1999-08       Impact factor: 1.066

3.  The dead donor rule.

Authors:  J A Robertson
Journal:  Hastings Cent Rep       Date:  1999 Nov-Dec       Impact factor: 2.683

4.  Outcome of transplantation of organs procured from bacteremic donors.

Authors:  R B Freeman; I Giatras; M E Falagas; S Supran; K O'Connor; J Bradley; D R Snydman; F L Delmonico
Journal:  Transplantation       Date:  1999-10-27       Impact factor: 4.939

Review 5.  Care of the potential organ donor.

Authors:  Kenneth E Wood; Bryan N Becker; John G McCartney; Anthony M D'Alessandro; Douglas B Coursin
Journal:  N Engl J Med       Date:  2004-12-23       Impact factor: 91.245

6.  Severe brain injury to neurological determination of death: Canadian forum recommendations.

Authors:  Sam D Shemie; Christopher Doig; Bernard Dickens; Paul Byrne; Brian Wheelock; Graeme Rocker; Andrew Baker; T Peter Seland; Cameron Guest; Dan Cass; Rosella Jefferson; Kimberly Young; Jeanne Teitelbaum
Journal:  CMAJ       Date:  2006-03-14       Impact factor: 8.262

7.  Withdrawal and withholding of life support in the intensive care unit: a comparison of teaching and community hospitals. The Southwestern Ontario Critical Care Research Network.

Authors:  S P Keenan; K D Busche; L M Chen; R Esmail; K J Inman; W J Sibbald
Journal:  Crit Care Med       Date:  1998-02       Impact factor: 7.598

8.  Life support in the intensive care unit: a qualitative investigation of technological purposes. Canadian Critical Care Trials Group.

Authors:  D J Cook; M Giacomini; N Johnson; D Willms
Journal:  CMAJ       Date:  1999-11-02       Impact factor: 8.262

9.  National impact of pulsatile perfusion on cadaveric kidney transplantation.

Authors:  J F Burdick; J D Rosendale; M A McBride; H M Kauffman; L E Bennett
Journal:  Transplantation       Date:  1997-12-27       Impact factor: 4.939

10.  Organ donor management in Canada: recommendations of the forum on Medical Management to Optimize Donor Organ Potential.

Authors:  Sam D Shemie; Heather Ross; Joe Pagliarello; Andrew J Baker; Paul D Greig; Tracy Brand; Sandra Cockfield; Shaf Keshavjee; Peter Nickerson; Vivek Rao; Cameron Guest; Kimberly Young; Christopher Doig
Journal:  CMAJ       Date:  2006-03-14       Impact factor: 8.262

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  53 in total

1.  One or two types of death? Attitudes of health professionals towards brain death and donation after circulatory death in three countries.

Authors:  D Rodríguez-Arias; J C Tortosa; C J Burant; P Aubert; M P Aulisio; S J Youngner
Journal:  Med Health Care Philos       Date:  2013-08

2.  Kidney and liver transplants from donors after cardiac death: initial experience at the London Health Sciences Centre.

Authors:  Roberto Hernandez-Alejandro; Yves Caumartin; Cameron Chent; Mark A Levstik; Douglas Quan; Norman Muirhead; Andrew A House; Vivian McAlister; Anthony M Jevnikar; Patrick P W Luke; William Wall
Journal:  Can J Surg       Date:  2010-04       Impact factor: 2.089

3.  Is the Canadian health care system ready for donation after cardiac death? A note of caution.

Authors:  Christopher James Doig
Journal:  CMAJ       Date:  2006-10-10       Impact factor: 8.262

4.  Organ donation after cardiocirculatory death.

Authors:  Mohamed Y Rady; Joseph L Verheijde; Joan McGregor
Journal:  CMAJ       Date:  2007-06-05       Impact factor: 8.262

5.  Improving organ donation in Canada.

Authors:  David Hollomby; Marc Germain; Sam Shemie; Leah Hollins; Kimberly Young
Journal:  CMAJ       Date:  2007-04-10       Impact factor: 8.262

Review 6.  Kidney donation after cardiac death.

Authors:  Jacob A Akoh
Journal:  World J Nephrol       Date:  2012-06-06

Review 7.  A few realistic questions raised by organ retrieval in the intensive care unit.

Authors:  Olivier Lesieur; Liliane Genteuil; Maxime Leloup
Journal:  Ann Transl Med       Date:  2017-12

8.  Eligibility for organ donation following end-of-life decisions: a study performed in 43 French intensive care units.

Authors:  Olivier Lesieur; Maxime Leloup; Frédéric Gonzalez; Marie-France Mamzer
Journal:  Intensive Care Med       Date:  2014-08-05       Impact factor: 17.440

9.  Can we reduce ischemic cholangiopathy rates in donation after cardiac death liver transplantation after 10 years of practice? Canadian single-centre experience

Authors:  Kerollos Wanis
Journal:  Can J Surg       Date:  2019-02-01       Impact factor: 2.089

10.  Donation after cardiac death: a survey of university student opinions on death and donation.

Authors:  Ari R Joffe; Roisin Byrne; Natalie R Anton; Allan R deCaen
Journal:  Intensive Care Med       Date:  2008-08-01       Impact factor: 17.440

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