| Literature DB >> 7931265 |
Abstract
A modification of the [3H]-pargyline labelling technique is presented for determining the active-site concentration of monoamine oxidase in soluble preparations. Kinetic considerations show that the rate of reaction of MAO-A with low concentrations of free pargyline will be very much slower than that of MAO-B. Failure to use adequate reaction times for the concentration of pargyline added can lead to gross underestimation of the quantity of MAO-A present.Entities:
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Year: 1994 PMID： 7931265 DOI： 10.1007/978-3-7091-9324-2_6
Source DB: PubMed Journal: J Neural Transm Suppl ISSN： 0303-6995