| Literature DB >> 7929747 |
M A Pfaller1, Q Vu, M Lancaster, A Espinel-Ingroff, A Fothergill, C Grant, M R McGinnis, L Pasarell, M G Rinaldi, L Steele-Moore.
Abstract
MICs of fluconazole and amphotericin B were determined independently for 100 coded yeast isolates by each of six laboratories to determine reproducibility of results by using a colorimetric oxidation-reduction-based broth microdilution test. In addition, each site tested five quality control isolates on at least four different occasions during the study. Results agreed within a three-dilution range (mode +/- 1 log2 dilution) for 96.2% of fluconazole tests and 92.7% of amphotericin B tests. Agreement among tests with the quality control isolates was 99.4% with fluconazole and 98.6% with amphotericin B. These results indicate that the colorimetric microdilution method is reproducible among laboratories.Entities:
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Year: 1994 PMID: 7929747 PMCID: PMC263742 DOI: 10.1128/jcm.32.7.1625-1628.1994
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948