Literature DB >> 7927709

Construction of a BALB/c congenic mouse, C.C3H-Lpsd, that expresses the Lpsd allele: analysis of chromosome 4 markers surrounding the Lps gene.

S N Vogel1, J S Wax, P Y Perera, C Padlan, M Potter, B A Mock.   

Abstract

Development of a congenic BALB/c mouse strain that contains a segment of chromosome 4 including the Lpsd allele of the lipopolysaccharide (LPS)-hyporesponsive C3H/HeJ strain is presented. On the basis of LPS-induced spleen cell mitogenesis, macrophage tumor necrosis factor secretion, and tyrosine phosphorylation in vitro and lethality in galactosamine-sensitized mice in vivo, the C.C3H-Lpsd strain provides a model of LPS hyporesponsiveness that is comparable to that of the parental C3H/HeJ strain. Analysis of markers in this region indicates that length of the donor fragment is approximately 5.5 centimorgans. Thus, the C.C3H-Lpsd strain provides an important genetic tool for analysis of markers in this region and for examining functional effects of Lpsd expression on the BALB/c background.

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Year:  1994        PMID： 7927709      PMCID： PMC303130          DOI： 10.1128/iai.62.10.4454-4459.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  28 in total

1.  Macrophage sensitivity to endotoxin: genetic control by a single codominant gene.

Authors:  D L Rosenstreich; S N Vogel; A R Jacques; L M Wahl; J J Oppenheim
Journal:  J Immunol       Date:  1978-11       Impact factor: 5.422

2.  The genetic mapping of a defective LPS response gene in C3H/HeJ mice.

Authors:  J Watson; K Kelly; M Largen; B A Taylor
Journal:  J Immunol       Date:  1978-02       Impact factor: 5.422

3.  The response of recombinant inbred strains of mice to bacterial lipopolysaccharides.

Authors:  J Watson; R Riblet; B A Taylor
Journal:  J Immunol       Date:  1977-06       Impact factor: 5.422

4.  Polysyndactyly, a new mutant gene in the mouse.

Authors:  D R Johnson
Journal:  J Embryol Exp Morphol       Date:  1969-04

5.  Location of the Mup-a locus on mouse linkage group 8.

Authors:  J S Finlayson; D M Hudson; B L Armstrong
Journal:  Genet Res       Date:  1969-12       Impact factor: 1.588

6.  Linkage of one component of the major urinary protein complex of mice to the brown coat color locus.

Authors:  D M Hudson; J S Finlayson; M Potter
Journal:  Genet Res       Date:  1967-10       Impact factor: 1.588

7.  C57BL/10/CR mice: nonresponders to activation by the lipid a moiety of bacterial lipopolysaccharide.

Authors:  K P McAdam; J L Ryan
Journal:  J Immunol       Date:  1978-01       Impact factor: 5.422

8.  Characterization of a congenitally LPS-resistant, athymic mouse strain.

Authors:  S N Vogel; C T Hansen; D L Rosenstreich
Journal:  J Immunol       Date:  1979-02       Impact factor: 5.422

9.  Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 4.

Authors:  C M Abbott; R Blank; J T Eppig; F T Fiedorek; W Frankel; J M Friedman; K E Huppi; I Jackson; K Steel; B A Mock
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

10.  Genetic control of endotoxic responses in mice.

Authors:  J Watson; M Largen; K P McAdam
Journal:  J Exp Med       Date:  1978-01-01       Impact factor: 14.307
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  19 in total

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Authors:  Sang-Hoon Sin; Anthony B Eason; Rachele Bigi; Yongbaek Kim; SunAh Kang; Kelly Tan; Tischan A Seltzer; Raman Venkataramanan; Hyowon An; Dirk P Dittmer
Journal:  J Virol       Date:  2018-09-12       Impact factor: 5.103

2.  Differential innate immune cell signatures and effects regulated by toll-like receptor 4 during murine lung tumor promotion.

Authors:  Carla-Maria Alexander; Ka-Na Xiong; Kalpana Velmurugan; Julie Xiong; Ross S Osgood; Alison K Bauer
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3.  Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4.

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Journal:  J Atheroscler Thromb       Date:  2015-03-05       Impact factor: 4.928

4.  TLR4 is a critical regulator of angiotensin II-induced vascular remodeling: the roles of extracellular SOD and NADPH oxidase.

Authors:  Tadaaki Nakashima; Seiji Umemoto; Koichi Yoshimura; Susumu Matsuda; Shinichi Itoh; Tomoaki Murata; Tohru Fukai; Masunori Matsuzaki
Journal:  Hypertens Res       Date:  2015-04-09       Impact factor: 3.872

5.  Male CD81 knockout genotype disrupts Mendelian distribution of offspring.

Authors:  Whitney J Mordica; Ryan J Gallagher; Jenna L Kennedy; Stephen K Chapes
Journal:  Comp Med       Date:  2010-06       Impact factor: 0.982

6.  Bacterial induction of beta interferon in mice is a function of the lipopolysaccharide component.

Authors:  A Sing; T Merlin; H P Knopf; P J Nielsen; H Loppnow; C Galanos; M A Freudenberg
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

7.  A murine platelet-activating factor receptor gene: cloning, chromosomal localization and up-regulation of expression by lipopolysaccharide in peritoneal resident macrophages.

Authors:  S Ishii; Y Matsuda; M Nakamura; I Waga; K Kume; T Izumi; T Shimizu
Journal:  Biochem J       Date:  1996-03-01       Impact factor: 3.857

Review 8.  Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies.

Authors:  Urs A Boelsterli; Matthew R Redinbo; Kyle S Saitta
Journal:  Toxicol Sci       Date:  2012-10-22       Impact factor: 4.849

9.  Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4.

Authors:  Stephanie K Bunt; Virginia K Clements; Erica M Hanson; Pratima Sinha; Suzanne Ostrand-Rosenberg
Journal:  J Leukoc Biol       Date:  2009-03-04       Impact factor: 4.962

10.  Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis.

Authors:  Alison K Bauer; Jennifer Fostel; Laura M Degraff; Elizabeth A Rondini; Christopher Walker; Sherry F Grissom; Julie Foley; Steven R Kleeberger
Journal:  Mol Cancer       Date:  2009-11-19       Impact factor: 27.401
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